role Archives - Family Medicine News

Consortium to investigate role of neurofilament light chain in neurodegenerative diseases

13.04.2021 Health Problems

Clinical scientists at Washington University School of Medicine in St. Louis and University College London are collaborating with pharmaceutical companies AbbVie, Biogen, Bristol Myers Squibb and Roche to investigate the role of neurofilament light (NfL) chain in neurodegenerative diseases such as amyotrophic lateral sclerosis, Parkinson’s disease, Huntington’s disease and Alzheimer’s disease. NfL is a protein that provides structural support to […]

Pregnant Domino Kirke Steps Down From Doula Role After Claims of Racism

04.06.2020 Kids Health

Stepping away. Domino Kirke has decided to step away from Carriage House Birth, the doula company that she cofounded in 2010, following claims of racism. “As you all know, 3 days ago anti-racist educator and activist Shishi Rose called out Carriage House Birth and myself. This week has been about pausing so I can really get behind what I say […]

Probing the role of an inflammation resolution sensor in obesity and heart failure

20.11.2019 Health Problems

After heart attack injury, several fatty-acid-derived bioactive molecules—including one called resolvin D1—play an essential signaling role to safely clear inflammation and help repair heart muscle. The mechanism of how this resolution occurs is not well-understood. There is a receptor on the surface of many immune cells called ALX/FRP2, and in models of atherosclerosis, ALX/FPR2 is known to act as a […]

100-year-old scientific mystery solved: Researchers discover role of nuclear glycogen in non-small cell lung cancers

13.09.2019 Health Problems

Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung cancers. Published in Cell Metabolism, the research centers on the function of glycogen accumulation in the nucleus of a cell. Glycogen is known […]

Uncovering possible role of polyphosphate in dialysis-related amyloidosis

08.07.2019 Health Problems

Long-term dialysis treatment is tough on the body in many ways, but one of the most serious complications is dialysis-related amyloidosis, a disease characterized by abnormal buildup of protein aggregates—called amyloid fibrils—in joints, tissues and organs. Although there is no cure, recent research by Osaka University researchers sheds light on how amyloid fibrils form and aggregate, thereby allowing the identification […]

Inherited mutations may play a role in pancreatic cancer development

27.02.2019 Health Problems

A small, retrospective study has found that, in patients with particular pancreatic duct lesions, the presence of an inherited mutation in a pancreatic cancer susceptibility gene may increase the patients’ risk of developing pancreatic cancer. To verify these results and learn more about the development of this deadly cancer, the researchers recommend more genetic studies. Their hope—in line with the […]

Marijuana, cocaine may play role in young americans’ rising stroke rate

05.02.2019 Health Problems

The vast majority of strokes occur in people over 65, but the number of younger adults having strokes is rising. New research suggests growth in illegal drug use could be playing a role. Past research has shown higher cardiovascular death rates for young adults who used cocaine or marijuana. But the new study, presented next week at the American Stroke […]

Kidney-resident macrophages—a role for healing during acute kidney injury?

25.01.2019 Health Problems

During development in the womb, immune cells called macrophages go to the kidneys, and they remain there for life. Understanding the possible healing role for these macrophages after kidney damage may be crucial to helping treat patients who suffer acute kidney injury. Acute kidney injury, or AKI, is a devastating condition that develops in two-thirds of critically ill patients, and […]

A role for microRNAs in social behavior

18.12.2018 Health Problems

The recent discovery of microRNAs as key regulators of biological processes has fueled an explosion of research activity into their function in health and disease. Researchers have now uncovered a microRNA cluster that regulates synaptic strength and is involved in the control of social behaviour in mammals. The researchers presume that their discovery may point to new therapeutic strategies for […]

Bug that causes stomach cancer could play a role in colorectal cancer

10.10.2018 Health Problems

A bacterium known for causing stomach cancer might also increase the risk of certain colorectal cancers, particularly among African Americans, according to a study led by Duke Cancer Institute researchers. The finding, published online Oct. 5 in the journal Gastroenterology, describes an association between antibodies to H. pylori bacteria and an increased risk of colorectal cancers, although it does not […]

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