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The deadly yellow fever virus has the potential to spread into cities around the world where it previously hasn’t been seen, according to a new study led by St. Michael’s Hospital. Researchers led by Dr. Kamran Khan of St. Michael’s have mapped the worldwide pathways through which yellow fever virus could spread by analyzing global patterns of airline travellers, the […]
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Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer—and they’ve also proven they have a way to see that feature using PET imaging. The team found PARP inhibitors—a type of targeted therapy that kills cancer cells with mutations in their DNA repair […]
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Researchers identified novel chromosomal mutations and described their role in the development of resistance of Escherichia coli (E. coli) to broad-spectrum antibiotic fosfomycin, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Researchers from France studied the genetic basis of fosfomycin resistance in a panel of E. coli isolates and found that certain […]
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Madrid, Spain: West Nile virus (WNV), which is transmitted via mosquito bites, reemerged and spread to new territories of Greece in 2017 following a two-year hiatus in reported human cases, according to findings presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). During this reemergence, in the summer and early autumn of 2017, researchers diagnosed 45 […]
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For the first time, the history charting the world-renowned Avon Longitudinal Study of Parents and Children (ALSPAC), also known as Children of the ’90s, back to its beginnings has been made accessible. The work, made possible thanks to a Wellcome grant and a dedicated team of archivists from the University’s Special Collections, will mean that researchers can now access the […]
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A new study by Althea Campuzano, Ph.D. a student at The University of Texas at San Antonio, and Floyd Wormley, Jr., Professor of Biology and Senior Associate Dean for Research and Graduate Studies, sheds light on little-known fungal infections caused by the fungus Cryptococcus. There are currently no vaccines available for any fungal infection, which can be extremely deadly to […]
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A collaborative research team led by Ann Chahroudi, MD, PhD, of Emory University is recommending long-term clinical monitoring for infants infected with Zika virus early after birth. The recommendation is based on the team’s research results showing for the first time that postnatal Zika virus infection of rhesus macaque infants results in persistent abnormalities in brain structure and function as […]
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Physicians and researchers at the USC Roski Eye Institute have collaborated with other California institutions to show that a first-in-kind stem cell-based retinal implant is feasible for use in people with advanced dry age-related macular degeneration. The results of their phase I/IIa study, which was funded in part by the California Institute for Regenerative Medicine, were published today in Science […]
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A team of Rutgers University and international scientists has determined the molecular target and mechanism of the antibacterial drug fidaxomicin (trade name Dificid). Fidaxomicin was approved in 2011 for treatment of the CDC “urgent threat” bacterial pathogen Clostridium difficile (C. diff) and currently is one of two front-line drugs for treatment of C. diff. Fidaxomicin also exhibits potent antibacterial activity […]
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Purdue University scientists have found another pathway that Listeria uses to enter the bloodstream, suggesting that forms of the foodborne bacteria considered benign may be more dangerous than once thought. About 600 million people around the world contract listeriosis each year, with 420,000 dying, according to the World Health Organization. In the U.S., 1,600 people are infected each year, causing […]
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