Researchers identify protein that contributes to racial disparities in prostate cancer

Cancer researchers have long known that prostate cancer tends to be more common, more aggressive and more resistant to existing treatments in African-Americans than in Caucasian-Americans, but they’re only beginning to understand why. A Roswell Park Comprehensive Cancer Center study published today points to cellular factors that appear to be driving these disparities—mitochondrial differences that prevent formation of the cancer-killing […]

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Researchers 3-D bio-print a model that could lead to improved anticancer drugs and treatments

University of Minnesota researchers have developed a way to study cancer cells which could lead to new and improved treatment. They have developed a new way to study these cells in a 3-D in vitro model (i.e. in a culture dish rather than in a human or animal). In a paper recently published in Advanced Materials, Angela Panoskaltsis-Mortari, Ph.D., Vice […]

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Researchers factoring in how children learn mathematics

What is 72 multiplied by 12? While fourth-graders will focus on arriving at the correct answer, University of Nebraska-Lincoln researcher Carrie Clark wants to know what happens in the brain as they learn to solve the problem. Clark, assistant professor of educational psychology, is using functional MRI technology to capture brain activity while children learn mathematics. Housed at the Nebraska […]

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Researchers discover new type of blood vessel in the bones of mice

A team of researchers affiliated with multiple institutions across Germany has discovered a new type of blood vessel in mouse bones. In their paper published in the journal Nature Metabolism, the group describes making sample mouse bones transparent, as well as their microscopic properties. Christopher Ritchlin and Iannis Adamopoulos with the University of Rochester and the University of California, respectively, […]

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Researchers identify widespread brain alterations in children with callousness

Children with elevated levels of callous traits—such as a lack of remorse and disregard for other people’s feelings—show widespread differences in brain structure compared with children with lower levels of the traits, according to a new study published in Biological Psychiatry. The differences, which included large- and small-scale structural alterations, support the idea of callous traits as a neurodevelopmental condition. […]

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Researchers find the cause of and cure for brain injury associated with gut condition

Using a mouse model of necrotizing enterocolitis (NEC)—a potentially fatal condition that causes a premature infant’s gut to suddenly die—researchers at Johns Hopkins say they have uncovered the molecular causes of the condition and its associated brain injury. The discovery enabled the team to combine efforts with colleagues studying brain inflammation and to identify potential drugs that reverse the brain […]

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Researchers identify risk factors of advanced liver disease in cystic fibrosis patients

Children’s Hospital Colorado (Children’s Colorado) pediatric gastroenterologist, Michael Narkewicz, MD, recently shared results of the Prospective Study of Ultrasound to Predict Hepatic Cirrhosis in Cystic Fibrosis (PUSH), which sought to determine if liver ultrasounds could identify children and adolescents with cystic fibrosis who are at greater risk of developing advanced liver disease. The Cystic Fibrosis Liver Disease Network PUSH study […]

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Researchers find bacteria residing in guts of mice come from mother and remain nearly constant over many generations

A team of researchers at the University of California has found that bacteria residing in the guts of mice are mainly obtained from their mothers and their microbiome makeup remains nearly the same over many generations. In their paper published in the journal Science, the group describes their experiments with house mice and what they learned. Prior research has shown […]

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