Researchers find risk factors for unemployment with multiple sclerosis vary by age

A recent study by Kessler Foundation researchers explored numerous factors that contribute to the high unemployment rate among individuals of different ages with multiple sclerosis (MS). This is the first investigation to consider age within the context of disease- and person-specific factors affecting employment in MS. The article, “Unemployment in multiple sclerosis across the ages: How factors of unemployment differ […]

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Researchers developing new ‘DNA stitch’ to treat muscular dystrophy

A new therapeutic being tested by University of Alberta researchers is showing early promise as a more effective treatment that could help nearly half of patients with Duchenne muscular dystrophy (DMD). The treatment—a cocktail of DNA-like molecules—results in dramatic regrowth of a protein called dystrophin, which acts as a support beam to keep muscles strong. The protein is virtually absent […]

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Researchers identify one driver of melanoma spread

Using a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in lab-grown melanoma cells, a team led by a Johns Hopkins Kimmel Cancer Center researcher identified highly unstable RNA molecules in human melanomas, including a novel miR-211 target gene DUSP3. Ranjan J. Perera, Ph.D., associate professor of oncology at […]

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Researchers find new ways to improve CPR

An international research consortium, which included faculty members from the University of Minnesota Medical School, was able to identify what is likely an optimal combination of chest compression frequency and depth when performing CPR. The investigation was led by Sue Duval, Ph.D., Associate Professor of Medicine and Biostatistics at the U of M Medical School, assisted by an international team […]

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Researchers identify potential target for cardiac fibrosis treatment

A research team led by scientists from the Consortium for Fibrosis Research & Translation (CFReT) at the University of Colorado School of Medicine has identified a potential target for treating heart failure related to fibrosis. Fibrosis is a wound-healing response after tissue injury or stress. Cardiac fibrosis can cause abnormal stiffening of the heart, contributing to the pathogenesis of heart […]

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100-year-old scientific mystery solved: Researchers discover role of nuclear glycogen in non-small cell lung cancers

Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung cancers. Published in Cell Metabolism, the research centers on the function of glycogen accumulation in the nucleus of a cell. Glycogen is known […]

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Researchers develop method for identifying aggressive breast cancer drivers

Precision cancer medicine requires personalized biomarkers to identify patients who will benefit from specific cancer therapies. In an effort to improve the accuracy of predictions about prognosis for patients with breast cancer and the efficacy of personalized therapy, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a method to precisely identify individual patients who have aggressive breast […]

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Researchers discover new cause of cell aging

New research from the USC Viterbi School of Engineering could be key to our understanding of how the aging process works. The findings potentially pave the way for better cancer treatments and revolutionary new drugs that could vastly improve human health in the twilight years. The work, from Assistant Professor of Chemical Engineering and Materials Science Nick Graham and his […]

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