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Researchers have further analyzed a known signaling pathway they believe brings them one step closer to understanding the complex physiology of patients with chronic kidney disease (CKD), which might provide a path to new treatment options. CKD is a complex and unique condition that involves impaired removal of many different toxins from the blood. These toxins, which often are referred […]
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A Yale-led collaborative study boosts scientific understanding of how the lung disease idiopathic pulmonary fibrosis (IPF) progresses, providing a roadmap for researchers to discover new treatment targets for the disease. The study, led by Naftali Kaminski, M.D., the Boehringer-Ingelheim Endowed Professor of Internal Medicine and chief of the Section of Pulmonary, Critical Care, and Sleep Medicine at Yale School of […]
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Universitätsmedizin Berlin and the Medical University of Innsbruck have developed a new therapeutic concept for the treatment of temporal lobe epilepsy. It represents a gene therapy capable of suppressing seizures at their site of origin on demand. Having been shown to be effective in an animal model, the new method will now be optimized for clinical use. Results from this […]
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A computer screen, a blank wall and no window. That’s the uninspiring reality for millions of Australian office workers and students every day—and the perfect recipe for mental fatigue. But what if we injected a bit of nature, blue sky, greenery and a view in the office space? University of South Australia Ph.D. student Bridgette Minuzzo has done just that […]
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A technique using live human cancer tissue to develop the next generation of cancer drugs is being developed in South Australia. The researchers from the University of Adelaide are using the technique to fill the void between animal testing and clinical trials in a bid to cut the cost and time of drug development and reduce the failure rate in […]
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A new Mount Sinai study, published July 23 in the journal Nature Neuroscience, provides important insight into how microglia, cells that form a branch of the immune system inside the brain, go about their job of clearing out dying and non-functional neurons—and how they sometimes mistakenly attack healthy neurons, an event that can play a role in neurodegenerative diseases like […]
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Midgut neuroendocrine tumors are a rare type of cancer that develops in the small intestine and colon. Roughly 12,000 people are diagnosed with this disease each year. In January, the United Stated Food and Drug Administration approved Lutathera, a first-of-its-kind peptide receptor radionuclide therapy. The injection consists of a somatostatin analog combined with a radioactive isotope that directly targets neuroendocrine […]
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The multi-target small molecule anticancer drug nintedanib shows promising effectiveness in stopping the growth of human malignant pleural mesothelioma, a fatal thoracic tumor, in preclinical models, according to a new study published jointly by researchers in Austria, Germany and Hungary. Malignant pleural mesothelioma is a particularly aggressive tumor that occurs in the lining that covers the lungs. It typically results […]
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Accurately detecting a rare, but devastating cause of blindness in premature babies can be done as effectively with telemedicine as with traditional, in-person eye exams, a study published in JAMA Ophthalmology suggests. This is believed to be the first study to directly compare the two approaches. The finding could enable more blindness-preventing treatment for infants born in rural and other […]
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