New study provides rationale for use of a multi-target anticancer drug in patients with malignant pleural mesothelioma

The multi-target small molecule anticancer drug nintedanib shows promising effectiveness in stopping the growth of human malignant pleural mesothelioma, a fatal thoracic tumor, in preclinical models, according to a new study published jointly by researchers in Austria, Germany and Hungary. Malignant pleural mesothelioma is a particularly aggressive tumor that occurs in the lining that covers the lungs. It typically results […]

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Doctors in California Are Prescribing Food as Medicine, and It's Keeping Patients out of Hospitals

You are probably aware that healthy eating can prevent a lot of illnesses, but it turns out that receiving proper nutrition can actually make the chronically sick healthier too. That’s why some Medicaid patients suffering from chronic or life-threatening illnesses are now being prescribed food in addition to medicine. It’s part of an effort to increase health and reduce health […]

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Genetic counseling and testing proposed for patients with the brain tumor medulloblastoma

Researchers have identified six genes that predispose carriers to develop the brain tumor medulloblastoma and have used the discovery to craft genetic counseling and screening guidelines. The study appears today in the journal The Lancet Oncology. St. Jude Children’s Research Hospital, Hopp Children’s Cancer Center at the NCT Heidelberg (KiTZ), Germany, and The Hospital for Sick Children, Toronto, led the […]

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A new drug to help young patients with genetic obesity

In a new study, researchers from the Institute for Experimental Pediatric Endocrinology of the Charité – Universitätsmedizin Berlin have successfully treated patients whose obesity is caused by a genetic defect. Aside from its beneficial effects on the patients, the researchers also provided insights into the fundamental signaling pathways regulating satiety of the new drug. The results of this research have […]

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Gene study spots clues to heart risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol. The finding, published by the journal Circulation, helps explain why some patients experience a heart attack or the need for coronary revascularization to open blocked heart arteries while […]

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Study finds COPD patients are not learning how to properly use their inhaler devices

Inhaled medications play an important role in treating chronic obstructive pulmonary disease, or COPD, and it is imperative that the inhaler device be used properly to effectively treat the disease. However, in a recently released study in the Journal of the COPD Foundation, researchers from Baylor College of Medicine and other institutions found that healthcare providers and patients prioritize medication […]

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T cell biomarker predicts which CLL patients will respond to CAR T cell therapy

Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia (CLL) don’t respond to chimeric antigen receptor (CAR) T cell therapy, and the answer is tied to how primed patients’ immune systems are before the therapy is administered. While 80 percent of patients with advanced acute lymphoblastic leukemia (ALL) treated with the CAR T […]

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Obesity may hasten disability in patients with rheumatoid arthritis

In a study of adults with rheumatoid arthritis, those who were severely obese experienced more rapidly progressing disability than patients who were overweight. This was not explained by features of their arthritis, including the amount of inflammation in their joints. In the Arthritis Care & Research study, weight loss after enrollment was also associated with worsening disability, possibly as a […]

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Study shows a new approach to treating patients with stage IV Wilms tumor

A new study showing significantly improved survival rates for patients with stage IV Wilms tumors with lung metastases was recently published in the Journal of Clinical Oncology. The outcomes of the study, “Treatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children’s Oncology Group AREN0533 Study”, will be a game-changer in treating Wilms tumor […]

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Stories of child patients in early NHS unearthed

A University of Manchester historian is to highlight the untold experiences of children who were admitted to hospital in the early years of the NHS. In a special lecture on April 24 supported by the NHS Confederation—marking the NHS’s 70th anniversary of the launch of the National Health Service—Dr. Stephanie Snow will explore the human stories which define the NHS […]

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