Study help standardize use of therapeutic comas for epileptic patients

Status epilepticus, a dangerous condition in which epileptic seizures follow one another for a duration of five or more minutes without the victim’s regaining consciousness between them, is the second most common neurological emergency in the United States, with a recorded maximum of around 150,000-plus cases per year. In 60-70 percent of cases, the patient responds to antiepileptic medications and […]

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New treatment helps avoid deafness in child chemotherapy patients

An international trial has found that a medicine commonly used to treat poisoning is effective in reducing deafness in children receiving chemotherapy for cancer. University of Melbourne and Royal Children’s Hospital paediatric oncologist Professor Michael Sullivan was international vice chair of the study, results of which are published in today’s New England Journal of Medicine. Professor Sullivan said the trial […]

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Researchers identify method to diagnose cancer in patients with early onset diabetes

Patients diagnosed with pancreatic cancer can develop elevated blood sugar levels up to three years before their cancer diagnosis, according to the results of a study by Mayo Clinic researchers published the journal Gastroenterology. “Pancreatic cancer is rapidly fatal after its diagnosis, with average survival of six months,” says Suresh Chari, M.D., a gastroenterologist at Mayo Clinic. “It has also […]

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Thrombectomy in acute stroke therapy feasible for very old patients, but not without risks

Mechanical thrombectomy is an increasingly important therapy for acute stroke that can also benefit the very old – assuming a careful selection of patients and risk assessment. This is a finding of a Portuguese study presented at the 4th Congress of the European Academy of Neurology (EAN) in Lisbon. For several years now, the endovascular thrombectomy has been a way […]

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Sepsis-3 criteria ‘preferable’ in prognostication of critically ill patients

For almost 30 years, diagnostic criteria for sepsis has used the Systemic Inflammatory Response Syndrome (SIRS) criteria in those with suspected infection, with presence of two or more criteria being diagnostic of sepsis. Recently, the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) re-evaluated these definitions and introduced the Sequential (Sepsis-related) Organ Failure Assessment (SOFA) score, with an […]

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Older melanoma patients have better response to immune checkpoint blockade therapy

Patient age correlates with response to immunotherapy in melanoma and depleting regulatory T cells in young patients may have a therapeutic potential to enhance response in younger patients, according to research from The Wistar Institute. Study results were published online in Clinical Cancer Research. Immune checkpoint blockade therapy has been recently approved for treatment of melanoma based on its ability […]

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Newly-approved therapy provides improved quality of life for midgut neuroendocrine tumor patients

Midgut neuroendocrine tumors are a rare type of cancer that develops in the small intestine and colon. Roughly 12,000 people are diagnosed with this disease each year. In January, the United Stated Food and Drug Administration approved Lutathera, a first-of-its-kind peptide receptor radionuclide therapy. The injection consists of a somatostatin analog combined with a radioactive isotope that directly targets neuroendocrine […]

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Drones a lifesaver for cardiac arrest patients?

Drones, the unmanned aircraft that got its start as part of the U.S. military’s arsenal and is today being used by everyone from photographers to farmers, are now heralded as a solution to a problem that’s bedeviled emergency medical personnel for years: How to deliver lifesaving defibrillators to people suffering cardiac arrest in areas not quickly reached by ambulances. Experiencing […]

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Mobile health technology can potentially transform how patients manage heart disease risk

Mobile health technology has the potential to transform the way we prevent and manage heart disease, but there are unanswered questions about how to optimize this technology and maintain engagement with patients, according to a review of randomized clinical trials published in the Canadian Journal of Cardiology. Cardiovascular disease is the leading cause of death worldwide. Recently, mobile health (mHealth) […]

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Chemoradiotherapy before surgery may extend lives of pancreatic cancer patients

Pancreatic cancer patients treated with chemotherapy and radiotherapy before surgery may live longer than those who have immediate surgery, according to unpublished clinical trial results. The research, funded by the Dutch Cancer Society, looked at patients who had pancreatic cancer that could be removed by surgery because their cancer had not spread from the pancreas. Patients who had chemoradiotherapy before […]

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