Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

Kidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression with an experimental drug called tivozanib compared to an alternative approved by the U.S. Food and Drug Administration, according to a City of Hope-led study. “This agent has shown in clinical trials to be effective in delaying cancer growth beyond established […]

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Autism-related genetic mutations occur in aging brains of Alzheimer’s patients

Researchers believe that autism is caused by mutations that occur sporadically in the egg or sperm or during pregnancy. Activity-dependent neuroprotective protein (ADNP) is a dominant gene whose de novo (during pregnancy) mutations are known to cause autism-related intellectual disabilities. A new Tel Aviv University study has found that ADNP mutations continue to occur in old age and accumulate in […]

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Intermittent fasting increases longevity in cardiac catheterization patients

While Intermittent fasting may sound like another dieting craze, the practice of routinely not eating and drinking for short periods of time has shown again to lead to potentially better health outcomes. In a new study by researchers at the Intermountain Healthcare Heart Institute in Salt Lake City, researchers have found that cardiac catheterization patients who practiced regular intermittent fasting […]

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Wearable and implantable devices may transform care for patients with kidney failure

A feature article appearing in an upcoming issue of CJASN highlights the potential of wearable and implantable devices for treating kidney failure. In their feature article, Shuvo Roy, Ph.D. (University of California, San Francisco) and his colleagues note that traditional hemodialysis performed in clinics has a number of shortcomings, with patients reporting burdens related to fatigue, poor sleep, inability to […]

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New way of measuring white blood cell function offers better insights to help patients with sepsis

Caring for a patient with sepsis requires walking a treatment tightrope. Clinicians must identify the pathogen that is causing a patient’s infection, carefully monitor the patient’s response to antibiotics and supportive measures and race against the clock to prevent potential organ failure and death. Most of the time, physicians can control the infection itself. What ultimately leads to multi-organ system […]

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Opioid-related cardiac arrest patients differ from other cardiac arrests

One recent study found that opioid overdose victims who suffer cardiac arrest are distinctly different from other cardiac arrest patients, yet they may be more likely than others to survive long enough to be admitted to a hospital, according to preliminary research to be presented at the American Heart Association’s Resuscitation Science Symposium 2019—November 16-17 in Philadelphia. “Cardiac arrests due […]

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What Is the TAVR Heart Procedure?

When the Rolling Stones announced the postponement of their 2019 tour because Mick Jagger was having health problems, fans were understandably disappointed and a little worried. Jagger is, after all, 75 years old, and when it became apparent that he was having heart surgery, the concern rose – but not for Dr. Joseph Cleveland. A heart surgeon and professor of […]

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The first test to detect dysphagia in patients with cognitive problems

Researchers from the Mind, Brain and Behaviour Research Centre (CIMCYC) of the University of Granada (UGR) have designed a test to detect dysphagia, a disorder that prevents people from swallowing when eating. It affects 8 percent of the world’s population. Dysphagia is prevalent among older people in particular (30 percent to 40 percent of the elderly people admitted to hospitals […]

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Certain genetic variants predispose patients with diabetes to kidney disease

In an unprecedented scale, researchers have begun to unravel the genetics that may predispose some individuals to develop kidney disease once they have diabetes, independent of the degree of blood sugar control. The findings appear in an upcoming issue of JASN. Many individuals with type 1 diabetes develop kidney disease despite adequate blood sugar control, while others maintain normal kidney […]

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Novel approach leads to potential sepsis prevention in burn patients

Immediately following severe burns, bacteria reach the wound from different sources, including the patient’s skin, gastrointestinal tract, respiratory tracts and health care-related human contact. Within the wound, bacteria multiply, establish an infection and move from the infected burn wound into the bloodstream, causing serious complications like sepsis, multiple-organ failure and death. In modern burn units, more than 50% of deaths […]

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