Greater efforts are needed to address ‘financial toxicity’ of cancer treatment

In addition to facing new concerns about their health, individuals who are diagnosed with cancer often worry about the financial burdens of treatment. A new study indicates that many patients feel that such ‘financial toxicity’ is not adequately addressed by their doctors and other clinicians. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer […]

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First practice guidelines for clinical evaluation of Alzheimer’s disease

Despite more than two decades of advances in diagnostic criteria and technology, symptoms of Alzheimer’s disease and Related Dementias (ADRD) too often go unrecognized or are misattributed, causing delays in appropriate diagnoses and care that are both harmful and costly. Contributing to the variability and inefficiency is the lack of multidisciplinary ADRD evaluation guidelines to inform U.S clinicians in primary […]

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The cause of prostate cancer progression to the incurable stage has likely been uncovered

Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism (SNP) rs11672691 influences prostate cancer aggressiveness. Their findings also suggest ways to improve risk stratification and clinical treatment for advanced prostate cancer. The study is published in the journal Cell. Three billion base pairs […]

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Switching to certain antidiabetic drugs linked to increased risk of major complications

For people with type 2 diabetes, switching to sulfonylurea drugs to control blood sugar levels is associated with an increased risk of complications compared with staying on the drug metformin, finds a study in The BMJ today. As such, the researchers say that continuing metformin when introducing sulfonylureas is safer than switching. Metformin is a “first-line” therapy (the first drug […]

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Study reveals long-term effectiveness of therapy for common cause of kidney failure

New research provides support for the long-term efficacy of a drug used to treat in patients with autosomal dominant polycystic kidney disease (ADPKD), a common cause of kidney failure. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The hormone vasopressin promotes the progression of ADPKD, the fourth leading cause of […]

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Risk of cochlear disorders up with history of migraine

(HealthDay)—The risk of cochlear disorders, especially tinnitus, is increased among patients with a history of migraine, according to a study published online July 12 in JAMA Otolaryngology-Head & Neck Surgery. Juen-Haur Hwang, M.D., Ph.D., from the Dalin Tzu Chi Hospital in Taiwan, and colleagues used claims data from the Taiwan Longitudinal Health Insurance Database 2005 to identify 1,056 patients with […]

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