Bioluminescent deep-sea creatures illuminate the effectiveness of new cancer therapies

Researchers at the Keck School of Medicine of USC have developed a new laboratory tool, which is poised to improve the development and effectiveness of a burgeoning group of therapies that use patients’ immune systems to fight cancer with genetically engineered CAR-T cells. Called the Topanga assay, the tool was inspired by the beauty of Topanga Beach in Malibu and […]

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New study proves the success of support for parents who have children taken into care

A scheme supporting parents who have had children taken into care has been praised by Cardiff University academics in charge of its first independent evaluation. Dr. Louise Roberts, from the Children’s Social Care Research and Development Centre (CASCADE), led the assessment of one of the first Reflect schemes, which has been run by Barnado’s Cymru in Gwent since 2016. Reflect […]

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True cost of gambling underestimated, say new publications

The current focus on individual ‘problem gamblers’ fails to take into account the full health and social cost of gambling because it overlooks the wider impact on families, friends and communities, according to new work published today. The joint work by Bangor University, Public Health Wales, Heather Wardle Research and Swansea University also shows that problem gambling rates are highest […]

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Team breaks new ground in study of malignant pediatric brain tumor

Scientists are making important progress in the battle against a class of devilishly complex human pediatric brain cancers thanks to a new study from a team of Florida State University students and faculty. Among young children, there’s no brain tumor more common than medulloblastoma. But no specific and effective therapy yet exists for this dangerous disease. Instead, doctors are forced […]

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Researchers discover new type of blood vessel in the bones of mice

A team of researchers affiliated with multiple institutions across Germany has discovered a new type of blood vessel in mouse bones. In their paper published in the journal Nature Metabolism, the group describes making sample mouse bones transparent, as well as their microscopic properties. Christopher Ritchlin and Iannis Adamopoulos with the University of Rochester and the University of California, respectively, […]

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Fighting deadly drug resistant bacteria in intestines with new antibiotic

A new antibiotic developed by a Flinders University researcher is being heralded as a breakthrough in the war against a drug resistant superbug. Bacteria are winning the fight against antibiotics as they evolve to fight off traditional treatments, threatening decades of advancements in modern medicine, with predictions they will kill over 10 million people by 2050. The scientific development of […]

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Discovery of enhanced bone growth could lead to new treatments for osteoporosis

UCLA and UC San Francisco life scientists have discovered a dramatic pattern of bone growth in female mice—research that could potentially lead to stronger bone density in women and new treatments for osteoporosis in older women. The researchers found that blocking a particular set of signals from a small number of neurons in the brain causes female, but not male, […]

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Research team documents potential new treatment path for breast cancer

Immunotherapies that take off the “brakes” on the adaptive anti-tumor response have worked well in melanoma and lung cancer but less so in breast cancers. That could change. A Vanderbilt team led by John Wilson, assistant professor of chemical and biomolecular engineering, and Rebecca Cook, associate professor of cell and developmental biology, activated innate immunity in breast cancer cells and […]

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New yeast model of metabolic disorders may lead to life-saving therapies

There are hundreds of metabolic disorders—including phenylketonuria, tyrosinemia, maple syrup urine disease and homocystinuria. These disorders lead to congenital diseases that produce a critical enzyme deficiency that interferes with the body’s metabolism. The pathologies and symptoms vary among the diseases, but all of them are usually fatal and have no known cure. Most metabolic disorders affect infants. The majority of […]

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