Obesity may hasten disability in patients with rheumatoid arthritis

In a study of adults with rheumatoid arthritis, those who were severely obese experienced more rapidly progressing disability than patients who were overweight. This was not explained by features of their arthritis, including the amount of inflammation in their joints. In the Arthritis Care & Research study, weight loss after enrollment was also associated with worsening disability, possibly as a […]

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Parents may help prep kids for healthier, less violent relationships

Warm, nurturing parents may pass along strategies for building and maintaining positive relationships to their kids, setting them up for healthier, less-violent romantic relationships as young adults, according to researchers. Researchers found that when adolescents reported a positive family climate and their parents using more effective parenting strategies—like providing reasons for decisions and refraining from harsh punishments—those adolescents tended to […]

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Posting your vacation online may make you forget it

(HealthDay)—Over the past decade, smartphones and social media have blanketed the planet like a technological tsunami. The result is that nearly 70 million new photos and 5 billion new posts are uploaded to Instagram and Facebook every day, respectively. But a new study suggests that constantly sharing the moments of your life online may undermine your ability to remember the […]

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PARP-1 may be key to effectiveness of PARP inhibitors, and now researchers can image it

Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer—and they’ve also proven they have a way to see that feature using PET imaging. The team found PARP inhibitors—a type of targeted therapy that kills cancer cells with mutations in their DNA repair […]

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Drinking kefir may prompt brain-gut communication to lower blood pressure

Drinking kefir may have a positive effect on blood pressure by promoting communication between the gut and brain. Kefir is a fermented probiotic milk beverage known to help maintain the balance of beneficial bacteria in the digestive system. Researchers will present their findings today at the American Physiological Society (APS) annual meeting at Experimental Biology 2018 in San Diego. Previous […]

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When others fail, new migraine treatment may work

People who have tried unsuccessfully to prevent migraine with other treatments may find relief with a drug called erenumab, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018. Migraine, which can be debilitating, is often very difficult to treat. As the […]

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New paper suggests that tumor cells may develop resistance to potential Ras inhibitors

Researchers have long sought a treatment aimed specifically at the Ras family of genes, the most common oncogenes and those that initiate many of the most lethal tumours. However, the results of a hypothetical treatment may be far less positive than speculated, according to a manuscript published in Genes & Development by the Genomic Instability Group at the Spanish National […]

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Drinking up to 3 cups of coffee per day may be safe, protective: study

Many clinicians advise patients with atrial or ventricular arrhythmias to avoid caffeinated beverages, but recent research has shown that coffee and tea are safe and can reduce the frequency of arrhythmias, according to a review published today in JACC: Clinical Electrophysiology. Arrhythmias, or abnormal heart rhythms, cause the heart to beat too fast, slow or unevenly. While some arrhythmias may […]

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