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Valerie Chang kept waking up breathless in the middle of the night. As a regular swimmer and non-smoker, she figured it was a fluke, a remnant of her childhood asthma, perhaps. But after a lung test, doctors told her that she had chronic obstructive pulmonary disease (COPD); her lung function was only 30 percent and she had done irreversible damage […]
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The InforMing the PAthway of COPD Treatment (IMPACT) study was conducted to assess the benefits of triple versus dual therapy in patients with COPD. In a study at CHEST, researchers found that regardless of baseline reversibility, the usage of triple dual therapies significantly reduced the annual rate and moderate-to-severe and severe exacerbations, improved lung function and overall quality of life […]
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Results of a 275-patient, multi-national phase III clinical trial known as ALTA-1L published today in the New England Journal of Medicine and presented concurrently in the press program at the International Association for the Study of Lung Cancer (IASLC) World Conference on Lung Cancer 2018 argue for brigatinib as a first-line treatment option for advanced ALK-positive non-small cell lung cancer. […]
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A new computer program can analyze images of patients’ lung tumors, specify cancer types, and even identify altered genes driving abnormal cell growth, a new study shows. Led by researchers at NYU School of Medicine and published online in Nature Medicine, the study found that a type of artificial intelligence (AI), or “machine learning” program, could distinguish with 97 percent […]
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Dear Mayo Clinic: Are there ever any early signs of lung cancer, or is it usually found only in the later stages? Can anything be done to prevent it other than not smoking? A: It’s rare for lung cancer to trigger symptoms before it progresses to its later stages. Most cases of early-stage lung cancer are detected by chance in […]
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Although national guidelines advise doctors to discuss the benefits and harms of lung cancer screening with high-risk patients because of a high rate of false positives and other factors, those conversations aren’t happening the way they should be, according to a study by researchers from the University of North Carolina Lineberger Comprehensive Cancer Center. Lung cancer screening is recommended for […]
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Regular cancer screenings can lower the chance of death from lung cancer. But they cannot reduce the risk of developing lung cancer for people who smoke. Patients seem to be confused about the actual benefits and limitations of lung cancer screenings, according to a study by the VA Center of Innovation for Veteran-Centered and Value-Driven Care in Seattle. Researchers asked […]
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Human lungs are coated with a substance called surfactant which allows us to breathe easily. When lung surfactant is missing or depleted, which can happen with premature birth or lung injury, breathing becomes difficult. In a collaborative study between Lawson Health Research Institute and Stanford University, scientists have developed and tested a new synthetic surfactant that could lead to improved […]
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Those who smoke are at the greatest risk of getting lung cancer, hence, for obvious reasons, those who don’t smoke assume they are not at risk at all. However, this is a misconception. Non-smokers can get lung cancer as well, just like any other cancer, and scientific research has narrowed down a few reasons why. Interestingly, smokers and ex-smokers tend […]
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A team of scientists led by University of Montana cell biologist Mark Grimes has identified networks inside lung cancer cells that will help understand this cancer and fight it with drug treatments. The paper, published as the cover article of the May 22 issue of Science Signaling, sheds light on how a new class of drugs called HSP90 inhibitors—which are […]
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