Loss of function in key Y-chromosome genes increases cancer risk in men

Numerous studies have shown that men are more susceptible to cancer than women; however, the reason for this difference remains poorly understood. A new study by researchers from the Barcelona Institute for Global Health (ISGlobal) has identified a key biological mechanism that puts men at higher risk of cancer: loss of function in certain genes of the sex-determining Y chromosome. […]

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Hear this: Healthful diet tied to lower risk of hearing loss

Investigators from Brigham and Women’s Hospital have found that eating a healthy diet may reduce the risk of acquired hearing loss. Using longitudinal data collected in the Nurses’ Health Study II Conservation of Hearing Study (CHEARS), researchers examined three-year changes in hearing sensitivities and found that women whose eating patterns more closely adhered to commonly recommended healthful dietary patterns, such […]

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Scientists discover new breakthrough in treatment for cancer hair loss

Scientists have determined a new way to protect the hair follicle from chemotherapy in an effort to prevent hair loss as a result of cancer treatments. Researchers based at The University of Manchester have discovered a new strategy for how to protect hair follicles from chemotherapy, which could lead to new treatments that prevent chemotherapy-induced hair loss—arguably one of the […]

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Loss of a DNA repair system creates a unique vulnerability in many cancer types

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes’ activity, in the process becoming dependent on those genes for their survival and growth. The resulting genetic dependencies may provide targets for developing new precision-guided drugs or other cancer treatment strategies. Reporting in Nature, researchers led by members of the Cancer Dependency […]

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Program aids weight loss in patients with mental illness

(HealthDay)—A behavioral weight loss intervention is effective among overweight and obese individuals with serious mental illness (SMI), regardless of their diabetes status, according to a study published online Feb. 14 in Diabetes Care. Eva Tseng, M.D., M.P.H., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues compared weight change from baseline to 18 months among participants with […]

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