Researchers 3-D bio-print a model that could lead to improved anticancer drugs and treatments

University of Minnesota researchers have developed a way to study cancer cells which could lead to new and improved treatment. They have developed a new way to study these cells in a 3-D in vitro model (i.e. in a culture dish rather than in a human or animal). In a paper recently published in Advanced Materials, Angela Panoskaltsis-Mortari, Ph.D., Vice […]

Continue reading »

Discovery of enhanced bone growth could lead to new treatments for osteoporosis

UCLA and UC San Francisco life scientists have discovered a dramatic pattern of bone growth in female mice—research that could potentially lead to stronger bone density in women and new treatments for osteoporosis in older women. The researchers found that blocking a particular set of signals from a small number of neurons in the brain causes female, but not male, […]

Continue reading »

New yeast model of metabolic disorders may lead to life-saving therapies

There are hundreds of metabolic disorders—including phenylketonuria, tyrosinemia, maple syrup urine disease and homocystinuria. These disorders lead to congenital diseases that produce a critical enzyme deficiency that interferes with the body’s metabolism. The pathologies and symptoms vary among the diseases, but all of them are usually fatal and have no known cure. Most metabolic disorders affect infants. The majority of […]

Continue reading »

Discovery may lead to safer drugs to save more women in childbirth

Postpartum hemorrhaging is the world’s leading cause of death for women during and after childbirth, and the third-leading cause in the United States alone. Many doctors in developing countries have turned to the drug misoprostol to save more women from deadly bleeding. Misoprostol, although affordable, has dangerous side effects, including uterine cramping, heart attack, toxicity in the brain and spinal […]

Continue reading »

In vitro cell culture findings could lead to novel interventions for schizophrenia

A study recently published in Translational Psychiatry, a Nature journal, has shown how using cultured cells from patients with psychotic disorders, such as schizophrenia, to investigate abnormalities in nerve connections in the brain could lead to new treatments. Strong correlations were observed between the findings in the cells in culture—grown outside the body in a controlled environment—and findings from brain […]

Continue reading »

Discovery of new neurons in the inner ear can lead to new therapies for hearing disorders

Researchers at Karolinska Institutet in Sweden have identified four types of neurons in the peripheral auditory system, three of which are new to science. The analysis of these cells can lead to new therapies for various kinds of hearing disorders, such as tinnitus and age-related hearing loss. The study is published in Nature Communications. When sound reaches the inner ear, […]

Continue reading »

Exposure to arsenic, lead, copper and cadmium linked to increased risk of heart disease

Exposure to arsenic, lead, copper and cadmium is associated with an increased risk of cardiovascular disease and coronary heart disease, finds a comprehensive analysis of the evidence published by The BMJ today. In recent years, exposure to environmental toxic metals such as arsenic, lead, copper, and mercury have become a major global health concern. Arsenic and cadmium, for example, are […]

Continue reading »

Discovery could lead to better treatment for leukemia

Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess this favorable mutation, but until now, how it helps improve outcomes has remained unknown. Scientists from the University of Illinois at Chicago report on how […]

Continue reading »

Dietary carbohydrates could lead to osteoarthritis, new study finds

Do your knees ache? According to new findings from the Oklahoma Medical Research Foundation, your diet could be a culprit. In a study led by OMRF scientist Tim Griffin, Ph.D., researchers found that the carbohydrate composition of diets increased the risk of osteoarthritis in laboratory mice—even when the animals didn’t differ in weight. “We know increased body fat elevates risk, […]

Continue reading »
1 2