New study provides insight into chronic kidney disease

Researchers have further analyzed a known signaling pathway they believe brings them one step closer to understanding the complex physiology of patients with chronic kidney disease (CKD), which might provide a path to new treatment options. CKD is a complex and unique condition that involves impaired removal of many different toxins from the blood. These toxins, which often are referred […]

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Neuroscientists have gained new insight into how the brain predicts missing visual information

Neuroscientists at the University of Glasgow have gained new insight into how the brain predicts missing visual information when perceiving the outside world. The researchers, from the University’s Institute of Neuroscience and Psychology, discovered that our brains “sketch out” portions of scenes that are not visible—much like how an artist sketches out a scene before filling the remaining details. The […]

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Breaking down AGEs: Insight into how lifestyle drives ER-positive breast cancer

Poor diet and lack of exercise are associated with cancer development, but the underlying biology is not well understood. Advanced glycation end products (AGEs) could offer a biological link to help us understand how certain lifestyle behaviors increase cancer risk or lessen the likelihood that an anti-cancer therapy will be effective. AGE accumulation is the natural and unavoidable result of […]

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Study provides insight into how dying neurons control eating behaviors of the brain microglia

A new Mount Sinai study, published July 23 in the journal Nature Neuroscience, provides important insight into how microglia, cells that form a branch of the immune system inside the brain, go about their job of clearing out dying and non-functional neurons—and how they sometimes mistakenly attack healthy neurons, an event that can play a role in neurodegenerative diseases like […]

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New insight into widespread virus behind birth defects

A Northwestern Medicine study published in Developmental Cell provides new insights into how cytomegalovirus—a common virus in the herpes family—replicates within human cells, and identifies proteins that may be therapeutically targeted to suppress infection. Human cytomegalovirus (HCMV) is widespread around the world, infecting between 60 to 100 percent of all adults. There is currently no cure or vaccine for HCMV; […]

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