How maternal Zika virus infection results in newborn microcephaly

A new study led by researchers at Baylor College of Medicine revealed how in utero Zika virus infection can lead to microcephaly in newborns. The team discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons. The findings point at the possibility of developing therapeutic strategies to prevent microcephaly […]

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New survey shows link between comprehensive antibiotic stewardship programs and infection preventionist certification

Nearly half of all nursing homes do not have adequately trained infection prevention staff and their efforts to combat the over prescription of antibiotics are suffering as a result, according to a new study in the American Journal of Infection Control (AJIC), the journal of the Association for Professionals in Infection Control and Epidemiology. Elderly nursing home residents are more […]

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Engineering B cells to express pathogen-specific antibodies to protect against infection

Antibodies are currently in use to treat diseases that range from cancer to autoimmunity and are usually administered to patients in multiple doses, much like medical drugs. However, the production and storage of antibodies are comparatively more expensive, with considerable interest on finding alternative strategies to deliver them. In a recent study, Howell F. Moffett and an interdisciplinary research team […]

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National handwashing campaign reduces incidence of Staphylococcus aureus infection in Australia’s hospitals

Since its implementation in 2009, the National Australian Hand Hygiene Initiative (NHHI) has seen significant, sustained improvements in hand hygiene compliance among Australian healthcare workers, and reduced risks of potentially fatal healthcare-associated Staphylococcus aureus infection, according to new research being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Amsterdam, Netherlands (13-16 April), and published […]

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New therapy approach points to potential treatment of liver cancer patients with hepatitis B virus infection

Researchers from Duke-NUS Medical School, Singapore General Hospital (SGH) and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma (HCC), a commonly occurring liver cancer. The treatment was also individualised, as T cells that were engineered were specific to the patients. The approach […]

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Liver cancer patients can be treated for Hep C infection

A large, multi-center study refutes earlier suggestions that antiviral drugs for treating hepatitis C may lead to a higher recurrence of liver cancer. Researchers at UT Southwestern Medical Center studied the records of patients who had been successfully treated for liver cancer at 31 medical centers in North America, comparing those who were and were not given direct-acting antivirals for […]

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Sugars and microbiome in mother’s milk influence neonatal rotavirus infection

Using a multidisciplinary approach, an international team of researchers from several institutions, including Baylor College of Medicine, reveals that complex interactions between sugars and the microbiome in human milk influence neonatal rotavirus infection. Reported in the journal Nature Communications, this study provides new understanding of rotavirus infections in newborns and identifies maternal components that could improve the performance of live, […]

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