Elucidation of functional mechanism of ‘love hormone,’ oxytocin, at molecular level

Oxytocin is essential in activities of the social brain such as trust and love and in maternal bonding behaviors. It is produced in the brain and secreted into the circulation. Here, by analyzing maternal behaviors of RAGE gene-manipulated mice, oxytocin was found to be transported back to the brain, crossing the blood-brain barrier (BBB), an extremely effective barrier, by binding […]

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Hormone therapy not beneficial in subclinical hypothyroidism

(HealthDay)—Thyroid hormone therapy is not associated with improvements in general quality of life or thyroid-related symptoms in non-pregnant adults with subclinical hypothyroidism, according to a review published in the Oct. 2 issue of the Journal of the American Medical Association. Martin Feller, M.D., from the University of Bern in Switzerland, and colleagues conducted a systematic literature review to identify randomized […]

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Hormone helps reverse brain damage caused by obesity

The neurobiotechnology research team of the Universitat Jaume I (UJI) in Castellón, Spain, headed by professor Ana María Sánchez, has proven the positive effects of a vegetable hormone, reversing brain alterations caused by high-fat diets, type-2 diabetes, obesity and physical inactivity. The results of this work, developed by the Health Sciences Department, have been published in Molecular Neurobiology. “We have […]

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Hormone therapy can make prostate cancer worse, study finds

Scientists at Cedars-Sinai have discovered how prostate cancer can sometimes withstand and outwit a standard hormone therapy, causing the cancer to spread. Their findings also point to a simple blood test that may help doctors predict when this type of hormone therapy resistance will occur. Prostate cancer is the second-leading cause of cancer death in men, behind lung cancer, killing […]

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Blocking digestive hormone may prevent diet-induced pancreatic cancer

A high-fat diet may promote the growth of pancreatic cancer independent of obesity because of the interaction between dietary fat and cholecystokinin (CCK), a digestive hormone. In addition, blocking CCK may help prevent the spread of pancreatic tumors to other areas of the body (metastases). The new findings are published ahead of print in the American Journal of Physiology—Gastrointestinal and […]

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Gene test for growth hormone deficiency developed

A new test developed by University of Manchester and NHS scientists could revolutionise the way children with growth hormone deficiency are diagnosed. Children suspected of having GHD – which cause growth to slow down or stop and other serious physical problems—currently require a test involving fasting for up to 12 hours. The fasting is followed by an intravenous infusion in […]

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How to fight side effects of hormone therapy for prostate cancer

Men on hormone therapy for prostate cancer may benefit significantly from hitting the gym with fellow patients and choosing more veggies and fewer cheeseburgers, a new study suggests. Androgen deprivation therapy is a powerful tool against prostate cancer, and more and more men are opting for the treatment as a growing array of hormone-based therapies become available. But it comes […]

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