Antibiotic-resistant bacteria found in the US presents a triple threat

Researchers from the Emory Antibiotic Resistance Center describe the first strain of carbapenem-resistant, hypermucoviscous Klebsiella pneumoniae exhibiting colistin heteroresistance and enhanced virulence isolated from a patient in the United States. The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology, held from June 7th to 11th, in Atlanta, Georgia. “The problem of antibiotic resistance […]

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Common diabetes drug found safe for most diabetics with kidney disease

Results of a large-scale study suggest that the oral diabetes drug metformin is safe for most diabetics who also have chronic kidney disease (CKD). The study of more than 150,000 adults by Johns Hopkins Medicine investigators found that metformin’s association with the development of a life-threatening condition called lactic acidosis was seen only among patients with severely decreased kidney function. […]

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Study characterizes proteins resulting from RAS gene mutations, found in more than 20 percent of all human cancers

When a RAS gene operates normally, it acts as an on/off switch for cell signaling to control cell proliferation. But when the gene mutates, the switch jams into the “on” position, allowing cells to proliferate uncontrollably. This unstoppable cascade inevitably leads to cancer. “The mutation in the gene is very common in pancreatic and colon cancer,” said Neil Kelleher, the […]

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