Novel gene mutation found in lymphatic disorder

Pediatric researchers have identified a gene mutation that causes a serious lymphatic condition, and used that knowledge to restore normal lymphatic vessels in model animals. The laboratory findings may lead to a new therapy for patients with this type of abnormal lymphatic circulation. “This discovery offers a potential avenue for intervening with existing drugs to treat patients with this complex, […]

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Chemicals found in vegetables prevent colon cancer in mice

Chemicals produced by vegetables such as kale, cabbage and broccoli could help to maintain a healthy gut and prevent colon cancer, a new study from the Francis Crick Institute shows. The research, published in Immunity, shows that mice fed on a diet rich in indole-3-carbinol—which is produced when we digest vegetables from the Brassica genus—were protected from gut inflammation and […]

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Liver cancer cell ‘switch’ found that could improve future therapies

Imperial researchers have found a new cell mechanism that could be used to target tumours in the future. The newly discovered ‘switch’ controls the activity of two proteins – ‘deleted in liver cancer-1’ (DLC1), a tumour suppressor, and talin. Both proteins control whether or not cancer cells spread to other parts of the body, but the exact mechanisms have remained […]

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Link found between resilience to dyslexia and gray matter in the frontal brain

Dyslexia, a reading disorder, is characterized by a difficulty in “decoding”—navigating between the visual form and sounds of a written language. But a subset of dyslexic people, dubbed “resilient dyslexics,” exhibit remarkably high levels of reading comprehension despite difficulties decoding. What is the precise mechanism that allows certain individuals with dyslexia to overcome their low decoding abilities and ultimately extract […]

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Proteins found in semen increase the spread of Ebola virus infection

Protein fragments, called amyloid fibrils, in human semen significantly increase Ebola virus infection and protect the virus against harsh environmental conditions such as heat and dehydration. Researchers from the Perelman School of Medicine at the University of Pennsylvania report these findings in a study published this week in the Proceedings of the National Academy of Sciences (PNAS). Although Ebola is […]

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Antibiotic-resistant bacteria found in the US presents a triple threat

Researchers from the Emory Antibiotic Resistance Center describe the first strain of carbapenem-resistant, hypermucoviscous Klebsiella pneumoniae exhibiting colistin heteroresistance and enhanced virulence isolated from a patient in the United States. The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology, held from June 7th to 11th, in Atlanta, Georgia. “The problem of antibiotic resistance […]

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