Three-minute version of brain stimulation therapy effective for hard-to-treat depression

In the largest study of its kind, a three-minute version of a brain stimulation treatment was shown to be just as effective as the standard 37-minute version for hard-to-treat depression. These results were published in a new Canadian study in The Lancet co-led by the Centre for Addiction and Mental Health (CAMH) and the University Health Network’s Krembil Research Institute, […]

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Prospects for new malaria interventions

April 25 marks World Malaria Day, an international event commemorated every year in recognition of global efforts to control malaria, one of the world’s oldest and deadliest diseases. This year’s theme, “Ready to beat Malaria”, underscores the collective goal and commitment of the global malaria community. In a recent review published in Open Biology, David Baker, Professor of Malaria Parasite […]

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Linear link for physical activity, amyotrophic lateral sclerosis

(HealthDay)—There is a linear correlation for physical activity (PA) with amyotrophic lateral sclerosis (ALS), according to a study published online April 23 in the Journal of Neurology, Neurosurgery & Psychiatry. Anne E. Visser, M.D., from the University Medical Center in Utrecht, Netherlands, and colleagues recruited patients with incident ALS and controls from five population-based registers in three European countries (Ireland, […]

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Radiotherapy offers new treatment option for liver cancer

A novel technique that delivers high doses of radiation to tumors while sparing the surrounding normal tissue shows promise as a curative treatment option for patients with early-stage liver cancer, according to a study published online in the journal Radiology. Curative treatment options for early-stage hepatocellular carcinoma (HCC), the most common type of liver cancer, include surgery, liver transplantation and […]

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Study reveals large differences in drug prescriptions for newborns between NICUs

Little is known concerning how extensively drugs are prescribed to newborns in different neonatal intensive care units (NICUs). A new British Journal of Clinical Pharmacology study of nearly 1,500 newborns admitted during 12 months to four different NICUs in The Netherlands found that drug use varies widely. Cardiovascular and nervous system drugs were most often prescribed off-label in relation to […]

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Seven-day antibiotic course delivers similar outcomes to 14-days for Gram-negative bacteraemia

A seven-day course of antibiotic treatment for Gram-negative bacteraemia (GNB), a serious infection that occurs when bacteria get into the bloodstream, was shown to offer similar patient outcomes as a 14-day course, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Researchers assessed several primary outcomes, including mortality and whether a patient was […]

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Targeted radiotherapy for breast cancer offers good quality of life and fewer side effects

Quality of life for women treated with a more targeted radiotherapy treatment – called accelerated partial breast irradiation – is at least as good as quality of life for women treated with standard radiotherapy, according to research presented at the ESTRO 37 conference and published simultaneously in The Lancet Oncology. The treatment uses small tubes to deliver a higher dose […]

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Brachytherapy for cervical cancer does not increase the risk of ureteral stricture

A rare but potentially serious complication following radiation treatment for cervical cancer is a narrowing of the tube (the ureter) that takes urine from the kidneys to the bladder, which can lead to kidney damage and sometimes life-threatening infections. This is called ureteral stricture and, until now, there have been concerns that brachytherapy might increase the risk, although the treatment […]

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