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EPO protects preemies’ brains by modifying genes essential for generating new brain cells

05.05.2018 Kids Health

Erythropoietin (EPO) helps to protect and repair vulnerable brains though it remains a mystery how the anemia drug does so. Genetic analyses conducted by a multi-institutional research team finds that EPO may work its neuroprotective magic by modifying genes essential for regulating growth and development of nervous tissue as well as genes that respond to inflammation and hypoxia. Findings from […]

Scientists reanimate disembodied pigs’ brains – but for a human mind, it could be a living hell

04.05.2018 Health Problems

Do you want to live forever? If so, there’s some good news. Or so it seems. For it appears that we may have taken a step closer to making immortality reality. In a recent meeting at the National Institutes of Health, Yale neuroscientist Nenad Sestan revealed that his team has successfully reanimated the brains of dead pigs recovered from a […]

Novel signal ID’d for microalbuminuria in europeans with T2DM

04.05.2018 Health Problems

(HealthDay)—A novel signal has been identified that is associated with microalbuminuria in Europeans with type 2 diabetes (T2D), according to a study published online April 27 in Diabetes. Natalie R. van Zuydam, Ph.D., from the University of Oxford in the United Kingdom, and colleagues conducted a genome-wide association study (GWAS) of diabetic kidney disease (DKD) in T2D using eight complementary […]

New approach for treating neuropathic pain

04.05.2018 Health Problems

Neuropathic pain is the chronic, pathological pain that continues even when the cause of pain is removed. Causes include damage to nerve cells and medicines used to treat cancer. A collaboration between research groups from Indiana University in Bloomington, USA and Turku Centre for Biotechnology in Finland has discovered a novel therapeutic that appears to interrupt the signaling cascades in […]

Scientists pinpoint neural interactions that are necessary for observational learning

03.05.2018 Health Problems

It’s often said that experience is the best teacher, but the experiences of other people may be even better. If you saw a friend get chased by a neighborhood dog, for instance, you would learn to stay away from the dog without having to undergo that experience yourself. This kind of learning, known as observational learning, offers a major evolutionary […]

The DES saga: Death risk high for young women exposed in utero

03.05.2018 Health Problems

A letter from three University of Chicago researchers in this week’s New England Journal of Medicine updates a 47-year-old series of reports on the risks of exposure during pregnancy to a supplement, diethylstilbestrol (DES), that was once widely used but since 1971 has been linked to a rare cancer: clear-cell adenocarcinoma of the vagina and cervix. In the May 3, […]

Research finds ‘Achilles heel’ for aggressive prostate cancer

02.05.2018 Health Problems

UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology. Experiments in mice and with human cells showed that blocking this stress response with […]

Study shows why bosses cut some employees slack for unethical behavior

02.05.2018 Health Problems

Imagine—or perhaps you don’t have to—that you’re at work and feeling very tired. You’re nearing the deadline on an important project, and you’ve stayed late at the office every day for weeks. Perhaps because you’re feeling so fatigued, when you submit an expense report for a recent lunch, you may round up just a smidge. Now imagine you are the […]

FDA approves CAR T therapy for large B-cell lymphoma

02.05.2018 Health Problems

The U.S. Food and Drug Administration (FDA) has expanded approval for a personalized cellular therapy developed at the University of Pennsylvania’s Abramson Cancer Center, this time for the treatment of adult patients with relapsed or refractory large B-Cell lymphoma after two or more lines of systemic therapy. Today’s approval includes treatment of diffuse large B-cell lymphoma (DLBCL) – the most […]

Evaluating drug regimens for high-risk prostate cancer

01.05.2018 Health Problems

The addition of a chemotherapy drug to adjuvant hormone therapy did not improve survival for patients with high-risk prostate cancer after surgery, according to the findings of a new clinical trial. The study, published in the Journal of Clinical Oncology, was led by Maha Hussain, MD, deputy director of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University and the Genevieve E. […]

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