Wearable and implantable devices may transform care for patients with kidney failure

A feature article appearing in an upcoming issue of CJASN highlights the potential of wearable and implantable devices for treating kidney failure. In their feature article, Shuvo Roy, Ph.D. (University of California, San Francisco) and his colleagues note that traditional hemodialysis performed in clinics has a number of shortcomings, with patients reporting burdens related to fatigue, poor sleep, inability to […]

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Study: Multidisciplinary transplantation evaluation shows promise for older adults

Older adults with blood cancers can benefit from a team-based, holistic evaluation before undergoing transplantation, according to a new study published today in Blood Advances. The study, which reported on a multidisciplinary clinic (MDC) at the University of Chicago Medical Center, found that patients treated with this approach experienced better transplantation outcomes and survival rates. Most blood cancers that can […]

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Chemotherapy sometimes set the stage for drug-resistant leukemia at relapse

Chemotherapy has helped make the most common childhood cancer one of the most curable, but researchers have evidence that the treatment may also prime some patients for relapse. Results published in the journal Blood reported that treatment-induced mutations cause drug resistance in some patients whose acute lymphoblastic leukemia (ALL) returns. “Our study reveals the evolution dynamics of pediatric ALL, which […]

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Eva Mendes' Kids Dressed as Dorothy Again for Halloween: 'I'm Another Witch'

Happy Halloween! Eva Mendes dressed up with her daughters — in the same outfits they wear every year. “My kid did this,” the actress, 45, captioned her Wednesday, October 30, Instagram Story. “Another Halloween. Another Dorothy. And I’m another witch.” In the social media upload, the Hitch star started into the camera with green makeup covering her face. She wore […]

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Bag of words test for Alzheimer’s disease

A positive diagnosis of Alzheimer’s disease (AD) can only be made definitively postmortem. However, there are many symptoms that become apparent as the disease progresses and specialists can usually be quite certain of a diagnosis. However, as with many diseases, the later the diagnosis, the less successful medical interventions will generally be. New research published in the International Journal of […]

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New gene therapy for epilepsy provides on-demand release of endogenous substance

Universitätsmedizin Berlin and the Medical University of Innsbruck have developed a new therapeutic concept for the treatment of temporal lobe epilepsy. It represents a gene therapy capable of suppressing seizures at their site of origin on demand. Having been shown to be effective in an animal model, the new method will now be optimized for clinical use. Results from this […]

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Scientists identify brain circuit responsible for building memories during sleep

Neuroscientists at the University of Alberta have identified a mechanism that may help build memories during deep sleep. In a study published last month in eNeuro, the researchers focused on the role of the nucleus reuniens, an area of the brain that connects two other brain structures involved in creating memories and may co-ordinate their activity during slow-wave sleep. “Slow […]

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Psychiatric diagnoses ‘neither necessary nor sufficient’ for access to NHS care in UK

A new study, published in the Journal of Mental Health, finds psychiatric diagnoses are seldom used as entry criteria for NHS mental health services in the UK. Despite controversy over their validity, and the damage they can do to people who receive the labels, psychiatric diagnoses are usually argued to be essential for accessing care, determining treatment options, communicating between […]

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