Researchers identify a possible cause and treatment for inflammatory bowel disease

Inflammatory bowel disease (IBD) is a category of refractory inflammatory disease, of which ulcerative colitis (UC) and Crohn’s disease (CD) are the main types. Current studies suggest that IBD is a complex autoinflammatory disease determined by genetic and environmental factors, and is the major cause of gastrointestinal cancer. Because of its complex and refractory character, researchers have focused on determining […]

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New technique predicts which melanoma patients are at risk for cancer recurrence, spread

For most patients, melanoma begins with a small, pigmented spot on their skin that they notice starts to change. Many primary melanomas can be cured by having this lesion removed, but melanoma can also recur and spread; an analysis of the removed lesion can offer some information on the likelihood that the cancer will come back. Today, lesions are analyzed […]

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Specialist technique used to study drugs completed for first time during Ebola outbreak

A specialist technique used to study drugs has been completed for the first time during an outbreak of Ebola virus disease. The study published today in eBiomedicine was a collaboration of researchers from Sierra Leone and the University’s of Glasgow, Oxford, Cambridge and the Liverpool School of Tropical Medicine. It used pharmacokinetics—the measurement of the change in drug concentration in […]

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New study finds evidence for reduced brain connections in schizophrenia

Advances in scanning have allowed researchers for the first time to show lower levels of a protein found in the connections between neurons in the living brains of people with schizophrenia. The researchers, who conducted the scans at the psychiatric imaging facility at the Medical Research Council (MRC) London Institute of Medical Sciences, say these changes could underlie the cognitive […]

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Study finds potential new treatment for preventing PTSD

Research led by the Centre for Addiction and Mental Health (CAMH) published in the Journal of Clinical Investigation points to a groundbreaking discovery about a new potential treatment and prevention for post-traumatic stress disorder (PTSD). The research team, led by Dr. Fang Liu, Senior Scientist and Head of Molecular Neuroscience in CAMH’s Campbell Family Mental Health Research Institute, and Professor […]

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Survivors of childhood cancers at risk for shortened life span

(HealthDay)—Survivors of childhood cancer remain at risk for shorter life spans, especially when they receive radiotherapy, according to a study published online Jan. 2 in JAMA Oncology. Jennifer M. Yeh, Ph.D., from the Harvard Medical School in Boston, and colleagues conducted a microsimulation model of competing mortality risks using data from the Childhood Cancer Survivor Study on five-year survivors of […]

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Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer

Anthracyclines remain a cornerstone of breast cancer therapy in combination with new-generation targeted drugs such as trastuzumab. Both types of drugs are major culprits in chemotherapy-induced heart disease. A recent study showed that being overweight or obese was a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer, but it did not take into account related cardiac risk factors […]

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Researchers identify neurons responsible for rapid eye movements/REM during sleep

Rapid Eye Movement—not only the name of a successful American rock band, but also and not least a characteristic eye movement in paradoxical sleep, the stage with high dream activity. This sleep phase has a peculiarity: Although the muscle tone of the sleeping person is completely relaxed, the eyes suddenly move back and forth. The name “paradoxical sleep” is well […]

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