Recarbrio OK’d for complicated urinary tract, intra-abdominal infections

(HealthDay)—The antibacterial drug product Recarbrio (imipenem, cilastatin, and relebactam) has been approved to treat complicated urinary tract infections (cUTI) and complicated intra-abdominal infections (cIAI) in adults, the U.S. Food and Drug Administration announced. Recarbrio, a three-drug combination injection, is intended to be used for patients who have limited or no alternative antibacterial drugs to treat their infection, Ed Cox, M.D., […]

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Scientists map high-risk areas for hepatitis E

EPFL scientists have created the first world map of regions with the highest prevalence of the hepatitis E virus (HEV). They hope that their map—freely available online—will help governments and NGOs design more effective prevention campaigns based on reliable data, particularly when it comes to setting up refugee camps. The scientists’ research has just been published in Scientific Reports. In […]

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Too much screen time for the kids? Grandparents may also be complicit

Grandparents have long been associated with letting their grandchildren do things their parents would never permit. Candy. Extended bedtime. Too much television. Carefree fun. They like to spoil their grandchildren. A new study by Rutgers and other researchers finds that today’s grandparents are still true to their traditional fun-loving image—allowing their grandchildren, while under their supervision, to spend about half […]

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Researchers criticize study calling for expansion of genetic testing for breast cancer

Researchers at the University of Cambridge have criticised a recent study calling into question guidelines on genetic testing for hereditary breast cancer. In an article published in the Journal of Clinical Oncology in December 2018 entitled “Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle?”, 27 US researchers argued for expanded genetic testing in all […]

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New target for drug intervention in Alzheimer’s disease identified

Scientists at the University of Alabama at Birmingham have identified an enzyme in the brain that may be an intriguing target for interventions against Alzheimer’s disease and other dementias. The researchers suggest that the enzyme, a serine/threonine kinase known as LIMK1, may play an important role in the degradation of dendritic spines, the connections between neurons in the brain. In […]

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NIH launches large TB prevention trial for people exposed to multidrug-resistant TB

A large clinical trial to assess treatments for preventing people at high risk from developing multidrug-resistant tuberculosis (MDR-TB) has begun. The study is comparing the safety and efficacy of a new MDR-TB drug, delamanid, with the decades-old TB drug isoniazid for preventing active MDR-TB disease in children, adolescents and adults at high risk who are exposed to adult household members […]

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Criteria for bariatric surgery should consider more than just patient’s weight

Experts at the Ohio State University Wexner Medical Center and 45 worldwide scientific and medical societies are pushing to change national guidelines that would allow more patients with the chronic diseases of obesity and diabetes to be eligible for bariatric surgery. Obesity affects almost 40 percent of the population—or about 93 million adults—in the United States, according to the Centers […]

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