Anesthesia sends neurons down the wrong path in unborn rat babies

While there has long been discussion whether exposure to anesthesia affects brain development, new Rush University Medical Center research published in the journal Cerebral Cortex describes how prenatal anesthesia in rats seems to disrupt the “precisely choreographed” and timed migration of neurons to the area of the developing brain where thinking, memory and language occur. The finding further fuels the […]

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Breaking down AGEs: Insight into how lifestyle drives ER-positive breast cancer

Poor diet and lack of exercise are associated with cancer development, but the underlying biology is not well understood. Advanced glycation end products (AGEs) could offer a biological link to help us understand how certain lifestyle behaviors increase cancer risk or lessen the likelihood that an anti-cancer therapy will be effective. AGE accumulation is the natural and unavoidable result of […]

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Understanding Down syndrome opens door to Alzheimer’s prevention trials

Clinical trials for preventing Alzheimer’s disease in people with Down syndrome may soon be possible thanks to new research from King’s College London. The researchers found changes in memory and attention are the earliest signs of Alzheimer’s in Down syndrome, and these changes start in the early 40s. People with Down syndrome have an extremely high risk of developing Alzheimer’s […]

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