Circadian clock and fat metabolism linked through newly discovered mechanism

The enzyme Nocturnin, which governs daily tasks such as fat metabolism and energy usage, works in an entirely different way than previously thought, reported a team of researchers at Princeton University. The newly discovered mechanism reveals the molecular link between the enzyme’s daily fluctuations and its energy-regulating role in the body, according to a study published this week in Nature […]

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Biochemical compound responsible for blood pressure drop in sepsis is discovered

A study conducted by an international group of researchers has overturned the understanding of life-threatening inflammatory diseases such as sepsis, pointing to a biochemical agent that may be involved in the rapid decline in blood pressure that occurs in the advanced stage of sepsis and usually causes the patient’s death. This discovery could pave the way for novel therapeutic approaches. […]

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Body clock link to steroids discovered

Professor David Ray, from The University of Manchester, lead the research which found that out of 752 genes which regulate lungs in mice, 230 genes work only in the day and only 197 at night. And in the liver, where doctors have long thought that steroids are influential for many side effects, 1,702 genes regulate the organ in the day […]

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Mechanism that drives development of liver cancer brought on by non-alcoholic fatty liver disease discovered

A team of researchers from several institutions in China has found a mechanism that appears to drive the development of a type of liver cancer not caused by alcohol consumption. In their paper published in the journal Science Translational Medicine, the group describes their study of liver cancer in mouse models and what they found. Ngee Kiat Chua, Hudson Coates […]

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