New opioid speeds up recovery without increasing pain sensitivity or risk of chronic pain

Morphine and other opioid-based painkillers are very effective at treating pain initially, but studies have shown that the drugs can make patients more pain-sensitive, prolonging their discomfort and increasing their risks of developing chronic pain. A new type of opioid developed by researchers at Tulane University and the Southeast Louisiana Veterans Health Care System doesn’t have this side effect and […]

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Interaction between immune factors triggers cancer-promoting chronic inflammation

A Massachusetts General Hospital (MGH) research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic, cancer-promoting inflammation. In their report published in PNAS, the investigators demonstrate that elevated levels of the immune factor IL-33 and regulatory T cells (Tregs), which suppress the action of tumor-fighting immune […]

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Diaphragm linked to chronic low back pain, study shows

Researchers of the Physical Therapy and Medicine departments of the CEU Cardenal Herrera University recently published a study on patients with chronic, non-specific low back pain, in which they conducted the first clinical trial of the effectiveness of osteopathic manual therapy with or without specific techniques on the diaphragm. The results have been published in Archives of Physical Medicine and […]

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Chronic lymphocytic leukemia patient goes into remission thanks to single CAR T cell

The doctors who have spent years studying the case call it “a series of fortunate events.” What began as a remarkable response to chimeric antigen receptor (CAR) T cell therapy is now providing evidence about the human genome and immune response that could help turn gene therapy non-responders into responders. Researchers at the University of Pennsylvania’s Abramson Cancer Center say […]

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The brain’s frontal lobe could be involved in chronic pain, according to research

A University of Toronto scientist has discovered the brain’s frontal lobe is involved in pain transmission to the spine. If his findings in animals bear out in people, the discovery could lead to a new class of non-addictive painkillers. For 20 years, Min Zhuo, a professor of physiology in the Faculty of Medicine, has been intrigued by invisible pain, in particular chronic […]

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What causes chronic fatigue? What we know, don’t know and suspect

Around 200,000 people in Australia suffer from a debilitating illness often branded with the unfortunate name of chronic fatigue syndrome (CFS). I say “unfortunate” because this implies patients are simply tired, run-down, burnt-out or overly stressed. But myalgic encephalomyelitis, or ME/CFS as it is now more commonly called, is a serious and incapacitating disease that can have a devastating impact […]

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Women with pregnancy-related diabetes may be at risk for chronic kidney disease

Gestational diabetes may predispose women to early-stage kidney damage, a precursor to chronic kidney disease, according to a study by researchers at the National Institutes of Health and other institutions. The study appears in Diabetes Care. Gestational diabetes occurs only in pregnancy and results when the level of blood sugar is too high. The condition increases the risk for preterm […]

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Research offers insights into impact of chronic pain

Drawing on her personal and academic background, Dr. Godfrey’s research has revealed that chronic pain does not impair how people pay attention to threatening information or their ability to focus when distractions are present. Dr. Godfrey conducted several studies based on the assumption that chronic pain would impair the way people pay attention to information that is relevant to pain. […]

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Metabolic syndrome common with chronic hep B infection

(HealthDay)—Metabolic syndrome (MetS) is prevalent among patients with chronic hepatitis B (HBV) infection, according to a study published online March 29 in Diabetes Care. Mandana Khalili, M.D., from the University of California, San Francisco, and colleagues assessed prevalence of MetS and its influence on alanine aminotransferase (ALT) levels and fibrosis among a multiethnic North American cohort with chronic HBV infection […]

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