How DNA outside cells can be targeted to prevent the spread of cancer

Cell-free DNA (cfDNA) is DNA found in trace amounts in blood, which has escaped degradation by enzymes. Scientists from Tokyo University of Science, led by Prof Ryushin Mizuta, have now discovered exactly how cfDNA is generated. They also talk about the applications of DNase1L3—the enzyme mainly responsible for generating cfDNA—as a novel molecule to prevent the spread of tumors. Prof […]

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Researchers criticize study calling for expansion of genetic testing for breast cancer

Researchers at the University of Cambridge have criticised a recent study calling into question guidelines on genetic testing for hereditary breast cancer. In an article published in the Journal of Clinical Oncology in December 2018 entitled “Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle?”, 27 US researchers argued for expanded genetic testing in all […]

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Infrared imaging technology being developed to better detect breast cancer

Researchers have found a non-invasive, cost effective method that uses infrared technology to locate hard-to-find breast cancer tumors. For the 40-50% of women with dense breast tissue, where these tumors often hide, this technology could be the difference between early interventions or major surgery. Faculty and student researchers at Rochester Institute of Technology, and physicians from the Rochester Regional Health […]

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Exercise after surgery is important for lung cancer surgery recovery

Lung cancer patients who exercised after the surgery to remove their tumour experienced better fitness levels and strength in their leg muscles as well as less shortness of breath compared to those who did not, new research led by Curtin University has found. The research, published in the Cochrane Database of Systemic Reviews, examined whether exercise training was beneficial for […]

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Human-on-a-chip model tests cancer drug efficacy and toxicity for therapeutic index

A reconfigurable “body-on-a-chip” model could transform drug development by simultaneously measuring compound efficacy and toxicity, for both target cells and other organs, such as the heart and liver. These findings, published in Science Translational Medicine, demonstrate the ability of a body-on-a-chip model to truly revolutionize biomedical research and personalized medicine through more accurate and efficient preclinical testing without the use […]

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Molecular analysis could improve the early detection and prevention of endometrial cancer

The use of molecular biomarkers in minimally invasive sampling opens a promising perspective for the early detection of endometrial cancer. This is the conclusion reached by the members of Screenwide research group, formed by researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute of Oncology (ICO-Hospitalet). The article that they have prepared, and that has been published […]

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