Conception by IVF may increase risk for rare childhood cancer

(HealthDay)—There is a small association between conception by in vitro fertilization (IVF) and childhood cancer, particularly hepatic tumors, according to a study published online April 1 in JAMA Pediatrics. Logan G. Spector, Ph.D., from the University of Minnesota in Minneapolis, and colleagues used data from the Society for Assisted Reproductive Technology Clinical Outcomes Reporting System on IVF cycles that resulted […]

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Loss of a DNA repair system creates a unique vulnerability in many cancer types

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes’ activity, in the process becoming dependent on those genes for their survival and growth. The resulting genetic dependencies may provide targets for developing new precision-guided drugs or other cancer treatment strategies. Reporting in Nature, researchers led by members of the Cancer Dependency […]

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Inhaled nanoparticles could treat lung cancer

QUT pharmaceutical scientist Dr. Nazrul Islam, from School of Clinical Sciences, said lung cancer was one of the most common cancers globally and one of the deadliest, being a leading cause of cancer deaths. He said chitosan had long been investigated for drug delivery and medical applications. It is made from refined crustacean (prawns, crabs, lobster) shells and was an […]

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Researchers develop treatment that turns tumors into cancer vaccine factories

Researchers at Mount Sinai have developed a novel approach to cancer immunotherapy, injecting immune stimulants directly into a tumor to teach the immune system to destroy it and other tumor cells throughout the body. The “in situ vaccination” worked so well in patients with advanced-stage lymphoma that it is also undergoing trials in breast and head and neck cancer patients, […]

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Metastatic prostate cancer may have its own biomarker, research finds

Prostate cancer can grow slowly and pose little threat to patients, or it can metastasize quickly, causing severe pain and death. But as of now, it’s nearly impossible to determine which type of cancer a patient has during the early stages. Now, University at Buffalo researchers and scientists from Moscow State University are collaborating to determine how a biomarker for […]

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New therapy approach points to potential treatment of liver cancer patients with hepatitis B virus infection

Researchers from Duke-NUS Medical School, Singapore General Hospital (SGH) and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma (HCC), a commonly occurring liver cancer. The treatment was also individualised, as T cells that were engineered were specific to the patients. The approach […]

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Scientists uncover novel strategy to target common type of cancer

Researchers have identified a protein critical for the survival of a particular type of tumor cell, according to a study published today in eLife. The findings, originally posted on bioRxiv, suggest that targeting a protein called Werner syndrome helicase (WRN) could represent a novel opportunity for treating a subgroup of cancer patients with microsatellite instability-high (MSI-H) tumors. MSI is a […]

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Cancer pain can be eased by palliative radiation therapy

Radiation therapy is, along with chemotherapy and surgery, one of the three main components of cancer treatment. It is often misunderstood and carries negative connotations. As radiation oncologists and assistant professors at Albert Einstein College of Medicine in New York and the University of British Columbia, we frequently work to dispel patients’ concerns about radiation —concerns that radiation treatment will […]

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