Researchers criticize study calling for expansion of genetic testing for breast cancer

Researchers at the University of Cambridge have criticised a recent study calling into question guidelines on genetic testing for hereditary breast cancer. In an article published in the Journal of Clinical Oncology in December 2018 entitled “Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle?”, 27 US researchers argued for expanded genetic testing in all […]

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Infrared imaging technology being developed to better detect breast cancer

Researchers have found a non-invasive, cost effective method that uses infrared technology to locate hard-to-find breast cancer tumors. For the 40-50% of women with dense breast tissue, where these tumors often hide, this technology could be the difference between early interventions or major surgery. Faculty and student researchers at Rochester Institute of Technology, and physicians from the Rochester Regional Health […]

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Genetic test for breast cancer helps women decide if preventive cancer treatment is right for them

A new study by University of Manitoba, CancerCare Manitoba and Mayo Clinic researchers has found that when women at high risk are provided with the results of genetic testing, they are more likely to take preventive medications to reduce their chances of developing breast cancer. Studies have shown that the risk of breast cancer can be reduced by half using […]

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Global HER2 testing survey raises questions about priorities for breast cancer resources

A global survey of HER2 testing has raised questions about how resources should be spent on potentially lifesaving HER2 targeted therapies for breast cancer, especially in poorer countries. The results were presented at the ESMO Breast Cancer Congress 2019, Berlin, 2-4 May 2019. The ONCOLLEGE-001 internet-based survey of HER2 testing in 45 countries has highlighted major access and affordability issues […]

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Diet high in leucine may fuel breast cancer’s drug resistance

About one in eight women in the United States will develop breast cancer in their lifetime. The vast majority of these cancers rely on the hormone estrogen to grow. Estrogen-receptor positive (ER+) breast cancer tumors are frequently treated with the drug tamoxifen, which blocks the hormone’s effect on the tumor. However, many tumors eventually become resistant to tamoxifen, allowing cancer […]

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Obesity and alcohol responsible for nearly 30,000 cases of breast cancers in the next decade

Maintaining a healthy weight and not consuming alcohol regularly could help prevent thousands of breast cancer cases, a new big data study by UNSW Sydney researchers has found. The findings could help inform future cancer control strategies. The large collaborative study led by UNSW’s Centre for Big Data Research in Health was published in the International Journal of Cancer. It […]

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Important signaling pathway in breast cancer revealed

Researchers at Kanazawa University report in Proceedings of the National Academy of Sciences (PNAS) that a particular signaling pathway in breast cancer tumors causes cancer cells to divide symmetrically, expanding the tumor. Inhibiting the pathway with drugs could become a strategy for eliminating the cancer cells. In breast cancer, one of the most common cancers in women, tumors contain a […]

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Research team documents potential new treatment path for breast cancer

Immunotherapies that take off the “brakes” on the adaptive anti-tumor response have worked well in melanoma and lung cancer but less so in breast cancers. That could change. A Vanderbilt team led by John Wilson, assistant professor of chemical and biomolecular engineering, and Rebecca Cook, associate professor of cell and developmental biology, activated innate immunity in breast cancer cells and […]

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Breast cancer up to five times more likely to metastasize even 10 years after childbirth

A study by researchers at University of Colorado Cancer Center and Oregon Health & Science University published today in the Journal of the American Medical Association Network shows that breast cancers diagnosed in young women within 10 years of giving birth are more likely to metastasize, and thus more likely to cause death, than breast cancers in young women who […]

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