Broken brain cells repaired in dementia mouse model

Dysfunctional neurons in the hippocampus of adult female mice modeling dementia can be repaired and reconnected to distant parts of the brain, reports a new study published in JNeurosci. The similarity between the mouse model and the human condition underscores the therapeutic potential of targeting these cells in dementia patients. The hippocampus generates new brain cells throughout life and is […]

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Dietary fats entering the brain may explain link between obesity and depression

Obesity and depression have long been linked, with previous clinical studies finding an association between these two conditions. However, until now, the mechanisms of how obesity affects depression and vice versa have not been fully understood. Now, in a new study led by the University of Glasgow in collaboration with the Gladstone Institutes, and published today in Translational Psychiatry, scientists […]

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Gender impacts brain activity in alcoholics

Compared to alcoholic women, alcoholic men have more diminished brain activity in areas responsible for emotional processing (limbic regions including the amygdala and hippocampus), as well as memory and social processing (cortical regions including the superior frontal and supramarginal regions) among other functions. In 2015, the National Survey on Drug Use and Health Alcoholism found 15.1 million adults have Alcohol […]

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Inhaled hydrogen could protect the brain during heart-lung bypass

Newborns with life-threatening congenital heart disease often need open-heart surgery with cardiopulmonary bypass, which carries a risk of damaging the brain. Critically ill newborns who are placed on ECMO are at even higher risk for brain injury. Hypothermia, or cooling the body, can improve neurologic outcomes, but has limitations. A new study in a large animal model, published April 29th […]

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Scientists restore some functions in a pig’s brain hours after death

Circulation and cellular activity were restored in a pig’s brain four hours after its death, a finding that challenges long-held assumptions about the timing and irreversible nature of the cessation of some brain functions after death, Yale scientists report April 18 in the journal Nature. The brain of a postmortem pig obtained from a meatpacking plant was isolated and circulated […]

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Deep stimulation improves cognitive control by augmenting brain rhythms

In a new study that could improve the therapeutic efficacy of deep-brain stimulation (DBS) for psychiatric disorders such as depression, a team of scientists shows that, when DBS is applied to a specific brain region, it improves patients’ cognitive control over their behavior by increasing the power of a specific low-frequency brain rhythm in their prefrontal cortex. The findings, published […]

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