PPIs combined with oral anticoagulants reduce risk of gastrointestinal bleeding

A Vanderbilt University Medical Center (VUMC) study published today in JAMA shows that patients already at higher risk for gastrointestinal bleeding gain a marked protection from this risk when they take a proton pump inhibitor (PPI) in combination with an oral anticoagulant. Oral anticoagulants, which prevent blood clot formation, are among the most widely prescribed medications in the United States. […]

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Most postmenopausal bleeding not associated with cancer

(HealthDay)—Most women with postmenopausal bleeding (PMB) will not be diagnosed with endometrial cancer, according to a review published online Aug. 6 in JAMA Internal Medicine. Megan A. Clarke, Ph.D., from the National Cancer Institute in Rockville, Md., and colleagues conducted a systematic literature review and meta-analysis to provide a reference of the prevalence of PMB in endometrial cancers and the […]

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GI bleeding research points to need for updated Medicare policies

Penn Medicine researchers are calling for greater precision in Medicare performance reporting for patients with gastrointestinal (GI) bleeding following an evaluation of patients with the condition. GI bleeding results in significant complications, deaths, and healthcare costs in the United States. This year, a new Medicare inpatient reporting program was implemented to assess patients with GI bleeding to better address quality […]

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