Interaction between immune factors triggers cancer-promoting chronic inflammation

A Massachusetts General Hospital (MGH) research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic, cancer-promoting inflammation. In their report published in PNAS, the investigators demonstrate that elevated levels of the immune factor IL-33 and regulatory T cells (Tregs), which suppress the action of tumor-fighting immune […]

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Interaction between two immune cell types could be key to better dengue vaccines, study shows

Researchers at Duke-NUS Medical School have demonstrated for the first time a physical interaction between two types of immune cells that plays an important role in the early fight against dengue virus infection. Dengue virus is widespread in the tropics and is transmitted by mosquitos. Dengue virus infection incidence has grown dramatically in recent years, with estimates suggesting 390 million […]

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How brains distinguish between self-touch and touch by others

The brain seems to reduce sensory perception from an area of skin when we touch it ourselves, according to a new study from Linköping University published in the journal Proceedings of the National Academy of Sciences. The finding increases the understanding of how the brain distinguishes between being touched by another person and self-touch. The ability to distinguish between self […]

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Breast cancer screening: New emphasis on shared decision-making between women and their doctors

An updated guideline on screening for breast cancer emphasizes shared decision-making between women and their doctors, supporting women to make an informed decision based on personal preferences when the balance between benefits and harms is uncertain. The guideline, released by the Canadian Task Force on Preventive Health Care, is published in CMAJ (Canadian Medical Association Journal). Based on the latest […]

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Study identifies link between DNA-protein binding, cancer onset

Researchers at the Stanford University School of Medicine and their collaborators at other institutions have identified a link between how proteins bind to our DNA and how cancer develops. This finding may allow researchers to predict cancer pathways and long-term patient outcomes. The research focuses on chromatin, the DNA-protein complex where all genes reside. Specifically, it evaluates chromatin’s relationship to […]

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Study confirms association between breastfeeding and lower risk of maternal hypertension

A new systematic review of the literature not only confirmed that breastfeeding for as short as 1-4 months can have a protective affect against high blood pressure in women, but that lactation also can protect women across an extended follow-up of years to decades. Among 15 studies reviewed that had longer-term follow-up, 67% of those evaluated for elevated blood pressure—and […]

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Health research discovers new link between hypoxia and blood clot risk

Research led by Rinku Majumder, Ph.D., Associate Professor of Biochemistry at LSU Health New Orleans School of Medicine, has found how hypoxia (a low concentration of oxygen) decreases Protein S, a natural anticoagulant, resulting in an increased risk for the development of potentially life-threatening blood clots (thrombosis). Although hypoxia has been associated with an increased risk for thrombosis, this research […]

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Link found between resilience to dyslexia and gray matter in the frontal brain

Dyslexia, a reading disorder, is characterized by a difficulty in “decoding”—navigating between the visual form and sounds of a written language. But a subset of dyslexic people, dubbed “resilient dyslexics,” exhibit remarkably high levels of reading comprehension despite difficulties decoding. What is the precise mechanism that allows certain individuals with dyslexia to overcome their low decoding abilities and ultimately extract […]

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