Researchers find bacteria residing in guts of mice come from mother and remain nearly constant over many generations

A team of researchers at the University of California has found that bacteria residing in the guts of mice are mainly obtained from their mothers and their microbiome makeup remains nearly the same over many generations. In their paper published in the journal Science, the group describes their experiments with house mice and what they learned. Prior research has shown […]

Continue reading »

New investigational antibiotic effective against drug-resistant bacteria in phase 2 trial

Results from a phase 2 randomised trial suggest that a new investigational antibiotic is as effective as the current standard-of-care antibiotic for the treatment of complicated urinary tract infections (UTIs) caused by several multidrug resistant Gram-negative bacteria. The findings, published in The Lancet Infectious Diseases, indicated that patients treated with the siderophore-based drug, cefiderocol, had a higher and more sustained […]

Continue reading »

Photoactive bacteria bait may help in fight against MRSA infections

Purdue University researchers are testing whether a light-active version of heme, the molecule responsible for transporting oxygen in blood circulation, may help people infected with MRSA. The research was published in the American Chemical Society journal ACS Infectious Diseases in September. The World Health Organization identifies MRSA as one of about a dozen antibiotic “superbugs” that pose an enormous threat […]

Continue reading »

Pneumonia-causing bacteria can be spread by nose picking and rubbing

Pneumonia-causing bacteria can be spread through picking and rubbing the nose, according to new research published in the European Respiratory Journal. Pneumococcus, the bacteria that can cause pneumonia, is known to be spread through inhalation of airborne droplets containing the bacteria, for example in coughs and sneezes. This study is the first to show that transmission can also occur via […]

Continue reading »

Hit ’em where they eat: Stealth drug fights resistant bacteria

The lack of new antibiotics is among the most critical challenges facing medicine. Researchers have been on the hunt for new drugs to combat “superbugs” that cannot be penetrated by current antibiotics. Rather than looking for drugs that forcibly penetrate bacteria, researchers tried a new approach: tricking bacteria into taking up a molecule that looks like food, but wreaks havoc […]

Continue reading »

Antibiotic-resistant bacteria found in the US presents a triple threat

Researchers from the Emory Antibiotic Resistance Center describe the first strain of carbapenem-resistant, hypermucoviscous Klebsiella pneumoniae exhibiting colistin heteroresistance and enhanced virulence isolated from a patient in the United States. The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology, held from June 7th to 11th, in Atlanta, Georgia. “The problem of antibiotic resistance […]

Continue reading »

Colistin-resistant multidrug-resistant bacteria pervasive in rural Vietnam town

A new study has found that the majority of residents in a rural village of Vietnam harbored multi-drug-resistant (MDR), colistin-resistant E. coli bacteria. Colistin is typically used as a last-resort treatment when there are no other therapy options available. The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology, held from June 7th to […]

Continue reading »

Killing bacteria by silencing genes may be alternative to antibiotics

A new approach to killing C. difficile that silences key bacterial genes while sparing other bacteria may provide a new way to treat the most common hospital-acquired bacterial infection in the United States, according to researchers. While conventional antibiotics treat bacterial infections, they can also cause a condition in the colon called C. difficile infection, due to the drug killing […]

Continue reading »
1 2