Drug treats inflammation associated with genetic heart disease that can be deadly in young athletes

When young athletes experiences sudden cardiac death as they run down the playing field, it’s usually due to arrhythmogenic cardiomyopathy (ACM), an inherited heart disease. Now, Johns Hopkins researchers have shed new light on the role of the immune system in the progression of ACM and, in the process, discovered a new drug that might help prevent ACM disease symptoms […]

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Fat mass index, not BMI, associated with cardiovascular events in people with diabetes

In people with diabetes, fat mass index, not body mass index (BMI), is associated with a higher risk of cardiovascular events, according to new research in CMAJ (Canadian Medical Association Journal). Heart disease is a major cause of death worldwide, and obesity is a major risk factor. Body mass index, a common measure of obesity, has been recently shown to […]

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‘Time-outs’ not associated with long-term negative effects in children

It’s an age-old debate: are time-outs bad for kids? Now, a new study suggests that despite sometimes getting a bad rap in the news, the common disciplinary strategy isn’t linked to harmful effects in children. Researchers compared emotional and behavioral health between kids whose parents reported using time-outs and those who didn’t over a roughly eight-year period. The result: no […]

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Discrimination of minorities associated with increased risk of psychosis

Discrimination of minority groups is likely to be associated with an increased risk of psychosis, according to a systematic review by University of Manchester and Lancaster psychologists. The review suggests that people perceiving discrimination on the basis of race, age, religion, sexuality or gender orientation are more likely to experience hearing voices, paranoia as well as common problems such as […]

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Test detects protein associated with Alzheimer’s and CTE

An ultrasensitive test has been developed that detects a corrupted protein associated with Alzheimer’s disease and chronic traumatic encephalopathy (CTE), a condition found in athletes, military veterans, and others with a history of repetitive brain trauma. This advance could lead to early diagnosis of these conditions and open new research into how they originate, according to National Institutes of Health […]

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Researchers find the cause of and cure for brain injury associated with gut condition

Using a mouse model of necrotizing enterocolitis (NEC)—a potentially fatal condition that causes a premature infant’s gut to suddenly die—researchers at Johns Hopkins say they have uncovered the molecular causes of the condition and its associated brain injury. The discovery enabled the team to combine efforts with colleagues studying brain inflammation and to identify potential drugs that reverse the brain […]

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Study discovers 40 new genetic variants associated with colorectal cancer risk

The most comprehensive genome-wide association study, or GWAS, of colorectal cancer risk to date, published today in Nature Genetics, has discovered 40 new genetic variants and validated 55 previously identified variants that signal an increased risk of colon cancer. The study, led by a team of investigators at Fred Hutchinson Cancer Research Center, also has identified the first rare protective […]

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