PPIs combined with oral anticoagulants reduce risk of gastrointestinal bleeding

A Vanderbilt University Medical Center (VUMC) study published today in JAMA shows that patients already at higher risk for gastrointestinal bleeding gain a marked protection from this risk when they take a proton pump inhibitor (PPI) in combination with an oral anticoagulant. Oral anticoagulants, which prevent blood clot formation, are among the most widely prescribed medications in the United States. […]

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