Mouse study mirrors human findings that link chemotherapy and APOE4 to cognitive issues

The research, led by Georgetown University Medical Center (GUMC) investigators and published in Neurotoxicity Research, complements findings from another GUMC-led study, published Oct. 3, that found a subset of breast cancer patients who experience long lasting cognitive deficits also have the APOE4 gene. Cancer survivors often report memory difficulties and this study, published in the Journal of Clinical Oncology (JCO), […]

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How astrophysics could transform the treatment of cystic fibrosis and other rare diseases

It’s a cruel disease which dramatically shortens life expectancy. One in 25 Europeans carry the cystic fibrosis gene and, in the UK, about 10,400 people currently have the condition. But people are living longer and longer thanks to improvements in screening at birth, early treatment and medication. One of the most important things is for patients to be put on […]

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Duvelisib has marked response, survival benefit in difficult-to-treat leukemia and lymphoma

For some patients with difficult-to-treat leukemia and lymphoma, the investigational oral medicine duvelisib may significantly improve disease outcomes, according to phase III trial data published today in the journal Blood. The DUO trial studied the head-to-head comparison of duvelisib versus ofatumumab, an approved standard-of-care chemotherapy for relapsed or treatment-resistant chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). According to […]

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Media violence, impulsivity and family conflict tied to aggressive behaviors in teenagers

Teenagers exposed to TV and film violence and high levels of household conflict are at risk of engaging in aggressive behaviors, according to a new study by researchers at three U.S. universities. Especially prone to aggressive tendencies are those who also have high levels of impulsivity, the six-member research team reported in a study published online ahead of print in […]

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Child protection investigations can silence children and offer impunity to abusers

The child protection investigation system in the UK is not fit for purpose. Despite high profile child abuse cases in Rochdale, Rotherham and Telford, lessons are not being learned and the failings of those investigations are being repeated. The Interim Report of the Independent Inquiry into Child Sexual Abuse found that two thirds of adults do not feel comfortable discussing […]

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Researchers glimpse into ‘real world’ of cancer and financial hardship

Nearly one in five older patients with advanced cancer have financial problems that may cause them to delay treatment to cover food and housing costs, which leads to stress and poor quality of life, according to new Wilmot Cancer Institute research. The “financial toxicity” study was conducted at several cancer clinics across the country, involving 542 patients ages 70 to […]

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Cooking with wood or coal is linked to increased risk of respiratory illness and death

Burning wood or coal to cook food is associated with increased risk of hospitalization or dying from respiratory diseases, according to new research conducted in China and published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. About three billion people around the world live in households that regularly burn wood, coal or other solid […]

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Here’s how Trump-era politics are affecting worker morale – and what managers can do about it

Pundits are projecting this year’s midterm elections to be nasty, polarizing and “epic.” They’re also expected to stress a lot of Americans out in every part of their lives. And that includes at the office. I recently conducted a study on a broad range of workplace issues, including how the stress of our increasingly divisive politics is affecting worker health, […]

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