Researchers aiming to cure spina bifida get a step closer to their goal

Researchers on the path to finding a cure for spina bifida have identified specific elements in stem cell secretions as key to protecting neurons and ultimately reducing the lower-limb paralysis associated with the birth defect. Those elements are exosomes—vesicles that transfer molecules from cell to cell—and a small carbohydrate-binding protein known as galectin 1. The team will use the results […]

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A new machine learning model can classify lung cancer slides at the pathologist level

Machine learning has improved dramatically in recent years and shown great promise in the field of medical image analysis. A team of research specialists at Dartmouth’s Norris Cotton Cancer Center have utilized machine learning capabilities to assist with the challenging task of grading tumor patterns and subtypes of lung adenocarcinoma, the most common form of the leading cause of cancer-related […]

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How Sweet! Chip, Joanna Gaines Donate Son Crew’s Bassinet to a Pregnant Fan

Chip and Joanna Gaines are giving back! The Fixer Upper stars — and real-life husband and wife — donated their youngest child’s bassinet to one lucky fan. “Uh oh.. what happens when they out grow the #snoo?? @happiest_baby,” Chip, 44, captioned an Instagram post in February that showed the couple’s 8-month-old son Crew looking too big for his bassinet. “Sell […]

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A cell atlas of the aging lung

Aging promotes lung function decline and increases susceptibility to diseases of the respiratory tract. In order to understand these effects in detail, researchers at Helmholtz Zentrum München, a partner in the German Center for Lung Research (DZL), analyzed the aging process in the lung at single-cell level using AI approaches. They have now presented this Atlas of the Aging Lung […]

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Is kidney failure a man’s disease?

A new analysis of the ERA-EDTA Registry reveals a striking gender difference in the incidence and prevalence of end-stage renal disease. Two thirds of all dialysis patients in Europe are male. It seems beyond hormonal effects that hypertension, diabetes and glomerulonephritis/sclerosis are the main driver of the gender gap. However, it is possible to prevent and treat hypertension and diabetes […]

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Inherited mutations may play a role in pancreatic cancer development

A small, retrospective study has found that, in patients with particular pancreatic duct lesions, the presence of an inherited mutation in a pancreatic cancer susceptibility gene may increase the patients’ risk of developing pancreatic cancer. To verify these results and learn more about the development of this deadly cancer, the researchers recommend more genetic studies. Their hope—in line with the […]

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New brain implants disguise as neurons, offering a potentially safer way to study and treat the brain

Like a well-guarded fortress, the human brain attacks intruders on sight. Foreign objects, including neural probes used to study and treat the brain, do not last long. But now, researchers have designed a probe that looks, acts, and feels so much like a real neuron that the brain cannot identify the imposters. According to Charles M. Lieber, this breakthrough “literally […]

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New nanomedicines for a more efficient and less aggressive treatment of prostate cancer

In Europe, prostate cancer is the most common type of cancer among men with an incidence greater than 100 cases per 100,000 individuals. Furthermore, it is currently the second most common cause of cancer-related deaths among men. This pathology mainly affects elderly men: nine in 10 deaths take place after 65 years of age. Therefore, it represents a very serious […]

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Genetic variations in a fourth gene linked to elevated leukemia risk in Hispanic children

St. Jude Children’s Research Hospital scientists have identified genetic variations in a fourth gene that are associated with an increased risk of acute lymphoblastic leukemia (ALL) in Hispanic children. The research appears today in the journal Blood. The gene is ERG, a transcription factor that is also mutated in the leukemic cells of some ALL patients. In this study, researchers […]

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Having a sense of meaning in life is good for you. So how do you get one?

The pursuit of happiness and health is a popular endeavour, as the preponderance of self-help books would attest. Yet it is also fraught. Despite ample advice from experts, individuals regularly engage in activities that may only have short-term benefit for well-being, or even backfire. The search for the heart of well-being – that is, a nucleus from which other aspects […]

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