New study provides rationale for use of a multi-target anticancer drug in patients with malignant pleural mesothelioma

The multi-target small molecule anticancer drug nintedanib shows promising effectiveness in stopping the growth of human malignant pleural mesothelioma, a fatal thoracic tumor, in preclinical models, according to a new study published jointly by researchers in Austria, Germany and Hungary. Malignant pleural mesothelioma is a particularly aggressive tumor that occurs in the lining that covers the lungs. It typically results […]

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Randomized trial finds ibuprofen not a safe alternative to antibiotics for UTIs

Ibuprofen, given instead of antibiotics to women with uncomplicated urinary tract infection, (cystitis), leads to longer duration of symptoms and more serious adverse events related to the spread of the primary infection, according to a new study in PLOS Medicine by Ingvild Vik and colleagues from the University of Oslo, Norway. More than half of all women will experience an […]

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Sun’s UV rays a threat to your eyes, too

(HealthDay)—It’s not just your skin that needs protection from ultraviolet rays, health experts warn. UV rays from the sun can cause corneal sunburn (photokeratitis) and UV damage that has been linked to macular degeneration, cataracts, cancer and pterygium (a growth on the white part of the eye), according to Prevent Blindness, a nonprofit eye health and safety group. The group […]

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New Mom Khloé Kardashian Says It's a 'Struggle Trying to Fit in Working Out Between Feedings'

Khloé Kardashian is getting her gym groove back! The Keeping Up with the Kardashians star used Snapchat Thursday to document her feelings following a post-pregnancy workout with her trainer — her first since giving birth to daughter True on April 12. Kardashian, 33, admitted to her followers that while she was “exhausted” following the sweat session, she was feeling positive and strong […]

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A holistic approach for mycetoma management

Mycetoma, a neglected tropical disease, can cause severe disfigurement and disability if not treated early. A holistic, community-based approach to detection and case management is effective at boosting disease prognoses, researchers now report in PLOS Neglected Tropical Diseases. Mycetoma can be caused by any of 70 fungi or actinomycetes bacteria. In all cases, chronic and progressive infection and inflammation cause […]

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Creating a compelling character to aid Latinas with depression and anxiety

For years, MarySue Heilemann, an associate professor at the UCLA School of Nursing, has worked with Latinas dealing with depression and anxiety, looking for ways to connect them to effective treatment. Then, she met media scholar Henry Jenkins at a UCLA/USC symposium. His groundbreaking insight into digital storytelling in the 21st century showed her that an audience can take an […]

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A new drug to help young patients with genetic obesity

In a new study, researchers from the Institute for Experimental Pediatric Endocrinology of the Charité – Universitätsmedizin Berlin have successfully treated patients whose obesity is caused by a genetic defect. Aside from its beneficial effects on the patients, the researchers also provided insights into the fundamental signaling pathways regulating satiety of the new drug. The results of this research have […]

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Scientists discover a new way to battle multiple sclerosis

Ridiculous. That’s how Andrew Caprariello says his colleagues described his theory about multiple sclerosis (MS) back when he was doing his PhD in Ohio. Caprariello’s passion to explore controversial new theories about MS propelled him to seek out a postdoctoral fellowship with a like-minded thinker, whom he found in University of Calgary’s Dr. Peter Stys, a member of the Hotchkiss […]

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Breast cancer: Discovery of a protein linked to metastasis

Jean-François Côté, a researcher at the Montreal Clinical Research Institute (IRCM) and professor at Université de Montréal’s Faculty of Medicine, studies metastasis, the leading cause of cancer-related death. Recently, his team uncovered a protein that, once deactivated, could prevent the development of metastases in an aggressive type of cancer, HER2-positive breast cancer. One in eight women will be diagnosed with […]

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