Genetically engineered 3-D human muscle transplant in a murine model

A growing need for tissues and organs in surgical reconstruction is addressed by the promising field of tissue engineering. For instance, muscle atrophy results from severe traumatic events including deep burns and cancer, requiring site/donor compatible surgical reconstruction. The existing ‘gold standard’ treatment in reconstructive surgery incorporates autologous flaps, although the technique is limited by low anatomical availability and donor […]

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Bug that causes stomach cancer could play a role in colorectal cancer

A bacterium known for causing stomach cancer might also increase the risk of certain colorectal cancers, particularly among African Americans, according to a study led by Duke Cancer Institute researchers. The finding, published online Oct. 5 in the journal Gastroenterology, describes an association between antibodies to H. pylori bacteria and an increased risk of colorectal cancers, although it does not […]

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Human hair cells from a test tube

Researchers from the University of Bern and Bern University Hospital have managed for the first time to differentiate human inner ear cells in a laboratory from somatic progenitors and to investigate their origin. This will make it possible to develop new treatment methods for hearing impairment in the future. About 5% of the world population suffers from hearing impairment. Disabling […]

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How to comfort a child whose sibling has died

In 1971, when I was four years old, my brother died of a congenital heart condition. Writing about this experience has prompted more responses than anything else I’ve ever written or spoken about. Untold and unheard stories appear in comments sections, strangers tell me cross-culturally consistent tales in the soft corners of conference rooms and speak about the siblings they’ve […]

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A Trojan Horse delivery for treating a rare, potentially deadly, blood-clotting disorder

In proof-of-concept experiments, University of Alabama at Birmingham researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP. The researchers deliver this therapeutic enzyme via the cellular equivalent of a Trojan Horse, using tiny blood cell platelets as their protective delivery vehicle, with a key enzyme hidden inside. TTP, or thrombotic thrombocytopenic purpura, appears as […]

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