Bioluminescent deep-sea creatures illuminate the effectiveness of new cancer therapies

Researchers at the Keck School of Medicine of USC have developed a new laboratory tool, which is poised to improve the development and effectiveness of a burgeoning group of therapies that use patients’ immune systems to fight cancer with genetically engineered CAR-T cells. Called the Topanga assay, the tool was inspired by the beauty of Topanga Beach in Malibu and […]

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Interaction between immune factors triggers cancer-promoting chronic inflammation

A Massachusetts General Hospital (MGH) research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic, cancer-promoting inflammation. In their report published in PNAS, the investigators demonstrate that elevated levels of the immune factor IL-33 and regulatory T cells (Tregs), which suppress the action of tumor-fighting immune […]

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Researchers 3-D bio-print a model that could lead to improved anticancer drugs and treatments

University of Minnesota researchers have developed a way to study cancer cells which could lead to new and improved treatment. They have developed a new way to study these cells in a 3-D in vitro model (i.e. in a culture dish rather than in a human or animal). In a paper recently published in Advanced Materials, Angela Panoskaltsis-Mortari, Ph.D., Vice […]

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Prostate cancer: Starving out the enemy

An old military tactic, widely used in Roman and medieval times, is now being put to good use in cancer research. The idea is that if you starve out your enemy—they will either submit or die. And in the race to develop treatments for prostate cancer, starving out those hostile cancer cells is proving effective. Metabolic biologist at the University […]

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New study proves the success of support for parents who have children taken into care

A scheme supporting parents who have had children taken into care has been praised by Cardiff University academics in charge of its first independent evaluation. Dr. Louise Roberts, from the Children’s Social Care Research and Development Centre (CASCADE), led the assessment of one of the first Reflect schemes, which has been run by Barnado’s Cymru in Gwent since 2016. Reflect […]

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Engineered DNA vaccine protects against emerging Mayaro virus

Infections by the mosquito-borne Mayaro virus (MAYV) have largely been restricted to people who ventured into the heavily forested areas of Trinidad and Tobago and neighboring regions of South America. However, recent laboratory studies showing additional mosquito vectors can transmit MAYV as well as a reported case of MAYV infection in Haiti in 2015, reveal the potential for the virus […]

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Beauty’s E-tail Race Heats Up in Europe

PARIS — As e-commerce gets the gold for the fastest-growing beauty channel today, competition is rife among sites vying in that increasingly crowded space in Europe, putting the squeeze on pure-play digital sellers such as Cult Beauty and Feelunique. Both platforms, based in the U.K., were on the block recently but have failed to find a buyer. Sources said Cult Beauty […]

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Interaction between two immune cell types could be key to better dengue vaccines, study shows

Researchers at Duke-NUS Medical School have demonstrated for the first time a physical interaction between two types of immune cells that plays an important role in the early fight against dengue virus infection. Dengue virus is widespread in the tropics and is transmitted by mosquitos. Dengue virus infection incidence has grown dramatically in recent years, with estimates suggesting 390 million […]

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