Mouse study links early metastasis to systemic inflammation caused by wound healing

According to new research conducted in mice by Whitehead Institute scientists, surgery in breast cancer patients, which while often curative, may trigger a systemic immunosuppressive response, allowing the outgrowth of dormant cancer cells at distant sites whose ability to generate tumors had previously been kept in check by the immune system. Taking a non-steroidal anti-inflammatory drug (NSAID) around the time […]

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Evaluating pediatric leukemia treatment

A drug called dasatinib was found to be safe and effective for children with chronic myeloid leukemia, according to a clinical trial published in the Journal of Clinical Oncology. Based on the findings, the drug has been approved by the FDA and is now available for use in some pediatric patients. The study was co-authored by Nobuko Hijiya, MD, professor […]

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Teachers can help reduce mental health problems in children, study finds

School-based mental health services delivered by teachers and staff can significantly reduce mental health problems in elementary-aged children, according to a new study by researchers at the Florida International University Center for Children and Families. The implications are significant considering approximately 30 to 40 percent of youth in the U.S. will be diagnosed with at least one mental health disorder […]

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Study may show how chronic early-life stress raises PTSD vulnerability

A collaboration between investigators at Massachusetts General Hospital and Khyber Medical University in Pakistan may have discovered how chronic stress experienced early in life increases vulnerability to post-traumatic stress disorder (PTSD) later in life. In their report published in Translational Psychiatry the researchers describe finding that chronic stress induces a persistent increase in the hormone ghrelin, both in a rat […]

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Mental disorders among leading causes of illness in children worldwide

While global rates of mental disorders in children have remained stable over time, the decline of infectious diseases will place mental disorders among the main causes of disease in children aged 4-15 years, according to a study published in the open access journal Child and Adolescent Psychiatry and Mental Health. Marie-Laure Baranne and Bruno Falissard at INSERM, France described the […]

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Scientists find excess mitochondrial iron, Huntington’s disease link

Scientists at the University of Wyoming have found that mice engineered to have Huntington’s disease (HD) have an over-accumulation of iron in their mitochondria. The research identifying a pathway for the neurodegenerative disease also has relevance to understanding related disorders such as Parkinson’s disease, Alzheimer’s and Lou Gehrig’s disease, says Jonathan Fox, a professor in UW’s Department of Veterinary Sciences. […]

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Guidance offered for improving mental health in workplace

(HealthDay)—Four recommendations for action have been developed for improving mental health in the workplace; the guidance forms the basis for an article published online in the April issue of the Journal of Occupational and Environmental Medicine. Ron Z. Goetzel, Ph.D., from the Johns Hopkins Bloomberg School of Public Health in Baltimore, and colleagues convened a public health summit and assembled […]

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Brain activity can predict success of depression treatment

McLean Hospital and Harvard Medical School researchers believe they have uncovered a method that could be useful in predicting a depressed patient’s treatment prognosis, prior to starting treatment. In the paper “Pretreatment Rostral Anterior Cingulate Cortex Activity in Relation to Symptom Improvement in Depression: A Randomized Clinical Trial,” currently available online and scheduled to appear in the June 2018 edition […]

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