Resetting the epigenetic balance for cancer therapy

Though mutations in a gene called MLL3 are common across many types of cancers, their relationship to the development of the disease has been unclear. Now, a Northwestern Medicine study has identified an epigenetic imbalance that silences the expression of tumor-suppressing proteins, allowing cancerous cells to proliferate. In the study published in Nature Medicine, Northwestern investigators applied a simple molecular […]

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Young toddlers may learn more from interactive than noninteractive media

Preschoolers can learn a lot from educational television, but younger toddlers may learn more from interactive digital media (such as video chats and touchscreen mobile apps) than from TV and videos alone, which don’t require them to interact. That’s the conclusion of a new article that also notes that because specific conditions that lead to learning from media are unclear, […]

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Robust immune responses for herpes zoster subunit vaccine

(HealthDay)—Recipients of the herpes zoster subunit vaccine (HZ/su), consisting of varicella-zoster virus glycoprotein E (gE) and AS01B Adjuvant System, develop robust immune responses, according to a study published in the June 1 issue of The Journal of Infectious Diseases. Anthony L. Cunningham, M.D., from the University of Sydney, and colleagues presented immunogenicity results from two trials involving patients aged 50 […]

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Scientists reveal likely cause of childhood leukaemia

A major new analysis reveals for the first time the likely cause of most cases of childhood leukaemia, following more than a century of controversy about its origins. Professor Mel Greaves from The Institute of Cancer Research, London, assessed the most comprehensive body of evidence ever collected on acute lymphoblastic leukaemia (ALL) – the most common type of childhood cancer. […]

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AUA: Most women report dysfunctional toileting behaviors

(HealthDay)—Many women report dysfunctional toileting behaviors, which are associated with lower urinary tract symptoms, according to a study presented at the annual meeting of the American Urological Association, held from May 18 to 21 in San Francisco. Casey G. Kowalik, M.D., from the Vanderbilt University Medical Center in Nashville, Tenn., and colleagues recruited 2,215 women to complete online questionnaires, including […]

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