Study provides insights into how fibrosis progresses in the human lung

A Yale-led collaborative study boosts scientific understanding of how the lung disease idiopathic pulmonary fibrosis (IPF) progresses, providing a roadmap for researchers to discover new treatment targets for the disease. The study, led by Naftali Kaminski, M.D., the Boehringer-Ingelheim Endowed Professor of Internal Medicine and chief of the Section of Pulmonary, Critical Care, and Sleep Medicine at Yale School of […]

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Many with atherosclerotic CVD not meeting LDL-C goals

(HealthDay)—A high proportion of patients with atherosclerotic cardiovascular disease (ASCVD) do not achieve recommended low-density lipoprotein cholesterol (LDL-C) goals, according to a study presented at the annual meeting of the American Heart Association, held from Nov. 16 to 18 in Philadelphia. Joseph Allen, from the American College of Cardiology in Washington, D.C., and colleagues examined LDL-C goal attainment (LDL-C

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Wearable and implantable devices may transform care for patients with kidney failure

A feature article appearing in an upcoming issue of CJASN highlights the potential of wearable and implantable devices for treating kidney failure. In their feature article, Shuvo Roy, Ph.D. (University of California, San Francisco) and his colleagues note that traditional hemodialysis performed in clinics has a number of shortcomings, with patients reporting burdens related to fatigue, poor sleep, inability to […]

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Jo Malone Cements Long-term Partnership With Zara, Launches Zara Emotions Collection by Jo Loves

LONDON — The perfumer Jo Malone has sniffed out another great opportunity in her long fragrance career, this time in the form of a long–term partnership with Zara, a first of its kind for the two. Malone has created a global fragrance collection of eight scents dubbed Zara Emotions Collection by Jo Loves, which launches Nov. 15. Available in Zara […]

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Practical Steps to Prevent Diabetes

So, do you want to hear the good news or the bad news first? Okay, here’s the bad news—type 2 diabetes is on the rise in the United States, with more than 100 million adults living with diabetes or prediabetes, according to a 2017 Centers for Disease Control and Prevention report. The good news? Type 2 diabetes can be prevented […]

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Restoring protein homeostasis improves memory deficits in Down syndrome model

Down syndrome is the most common genetic cause of intellectual disability, and currently there is no effective treatment. Memory deficits are a hallmark of this condition and a study published today in the journal Science reports that the defects in a conserved stress pathway dubbed the ‘integrated stress response,’ or ISR, could explain the cognitive deficits in a mouse model […]

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Zika virus can cause immune and brain abnormalities in asymptomatic pig offspring

Zika virus infection in the womb produces altered immune responses and sex-specific brain abnormalities in apparently healthy pig offspring, according to a study published november 14 in the open-access journal PLOS Pathogens by Uladzimir Karniychuk of the University of Saskatchewan, and colleagues. As noted by the authors, the findings could point to new strategies to prevent and alleviate the long-term […]

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