MRI resolution enhanced at cellular level

Neuroscience researchers have long used Magnetic Resonance Imaging to study the basic structure of the brain in health and disease, but MRI scanners can’t typically provide insights at the cellular level. In an MRI image, each voxel—the 3-D equivalent of a pixel—represents tens of thousands of brain cells. A breakthrough study led by the Mark and Mary Stevens Neuroimaging and […]

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Next-generation ALS drug silences inherited form of the disease in animal models

NIH-funded researchers delayed signs of amyotrophic lateral sclerosis (ALS) in rodents by injecting them with a second-generation drug designed to silence the gene, superoxide dismutase 1 (SOD1). The results, published in the Journal of Clinical Investigation, suggest the newer version of the drug may be effective at treating an inherited form of the disease caused by mutations in SOD1. Currently, […]

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New diagnostic blood test helps rule out need for CT scans in some patients with possible traumatic brain injuries

Research conducted at the Wayne State University School of Medicine has helped confirm the effectiveness of a blood biomarker that can indicate if patients with a head injury can avoid a costly CT scan because the blood test results indicate no traumatic brain injury (TBI). The findings, published online in The Lancet Neurology on July 24, validated the use of […]

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New strategy for cancer therapy spells double trouble for tumors

Scientists at Scripps Research have uncovered a new strategy to kill tumors, including some triple-negative breast cancers, without harming healthy cells, a discovery that could lead to more ways to treat tumors while reducing side effects. The study, published recently in Nature Communications, shows that a molecule in cells, called Rad52, repairs special kinds of damaged DNA that accumulate in […]

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Half of female students experience psychological distress, study shows

For the first time, just over 50 per cent of female students in Ontario show signs of moderate to serious psychological distress, according to the latest Ontario Student Drug Use and Health Survey (OSDUHS), released by Toronto’s Centre for Addiction and Mental Health (CAMH). Psychological distress—which refers to symptoms of anxiety or depression—has been rising steadily among all Ontario students […]

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Multiple pregnancies might make women’s cells ‘age’ faster

Multiple pregnancies might make women’s cells age more quickly, a new Northwestern University study suggests. Led by Calen Ryan and Christopher Kuzawa of Northwestern and Dan Eisenberg at the University of Washington, the research could help explain why women with many children tend to show signs of accelerated aging. The findings, published this week in Scientific Reports, were reached by […]

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Infection prevention staffing needs may be underestimated

(HealthDay)—A comprehensive assessment of health care organization composition and structure is necessary before determining infection preventionist (IP) staffing needs, according to a study published recently in the American Journal of Infection Control. Rebecca Bartles, M.P.H., from Providence St. Joseph Health System in Renton, Wash., and colleagues describe a large nonprofit health care system’s approach at quantifying the actual number of […]

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Link found between resilience to dyslexia and gray matter in the frontal brain

Dyslexia, a reading disorder, is characterized by a difficulty in “decoding”—navigating between the visual form and sounds of a written language. But a subset of dyslexic people, dubbed “resilient dyslexics,” exhibit remarkably high levels of reading comprehension despite difficulties decoding. What is the precise mechanism that allows certain individuals with dyslexia to overcome their low decoding abilities and ultimately extract […]

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