Blocking digestive hormone may prevent diet-induced pancreatic cancer

A high-fat diet may promote the growth of pancreatic cancer independent of obesity because of the interaction between dietary fat and cholecystokinin (CCK), a digestive hormone. In addition, blocking CCK may help prevent the spread of pancreatic tumors to other areas of the body (metastases). The new findings are published ahead of print in the American Journal of Physiology—Gastrointestinal and […]

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pH imbalance in brain cells may contribute to Alzheimer’s disease

Johns Hopkins Medicine scientists say they have found new evidence in lab-grown mouse brain cells, called astrocytes, that one root of Alzheimer’s disease may be a simple imbalance in acid-alkaline—or pH—chemistry inside endosomes, the nutrient and chemical cargo shuttles in cells. Astrocytes work to clear so-called amyloid beta proteins from the spaces between neurons, but decades of evidence has shown […]

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3D-printed implants shown to help grow ‘real bone’

Chemically coated, ceramic implants successfully guided the regrowth of missing bone in lab animals while “steadily dissolving,” researchers report. Surgeons and scientists at NYU School of Medicine and NYU College of Dentistry say their implanted scaffolds were naturally absorbed by the test animals’ bodies as new bone gradually replaced the devices. The research team describes its progress in a series […]

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Breast tissue tumor suppressor PTEN: A potential Achilles heel for breast cancer cells

In an article published July 17, 2018 by Nature Communications, a highly collaborative team of researchers at the Medical University of South Carolina (MUSC) and Ohio State University report that normal breast cells can prevent successful radiation treatment of breast cancer due to dysregulation between tumor suppressors and oncogenes. Tumor suppressors act like brakes that stop cells from undergoing uncontrolled […]

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buprenorphine

PHOENIX, July 27, 2018 (GLOBE NEWSWIRE) — INSYS Therapeutics, Inc. (NASDAQ: INSY) announced that today it received a Complete Response Letter (CRL) from the U.S. Food and Drug Administration (FDA) regarding the company’s New Drug Application (NDA) for a buprenorphine sublingual spray as a treatment for moderate-to-severe acute pain. Consistent with the outcome of an FDA Advisory Committee meeting in […]

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Acupuncture may cut arthralgia from aromatase inhibitors

(HealthDay)—Acupuncture may cut joint pain among postmenopausal women with early-stage breast cancer and aromatase inhibitor-related pain, according to a study published in the July 10 issue of the Journal of the American Medical Association. Dawn L. Hershman, M.D., from Columbia University in New York City, and colleagues evaluated acupuncture for reducing aromatase inhibitor-related joint pain among postmenopausal women with early-stage […]

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Sharing your #shopping on social media can damage your health and your wallet

Posting images on social media when we buy new clothes, eat out or purchase the latest gadget may seem harmless enough. But this consumption-oriented sharing may be undermining both our bank balance and our mental well-being. Our research has found that this sort of social media engagement is linked in some people to greater anxiety, lower self-esteem and an increased […]

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