Laser therapy increases survival in grim cancer diagnosis

People diagnosed with the aggressive brain cancer glioblastoma face a grim prognosis. Half die within 14 months of diagnosis. Even if initial treatment with surgery, radiation and chemotherapy is successful, such brain tumors typically recur, leaving patients with few options. Now, a research team at Washington University School of Medicine in St. Louis has found that laser treatment designed to […]

Continue reading »

Newly identified drug target in rheumatoid arthritis paves way for development of new therapies

University of Melbourne researchers have identified a protein involved in rheumatoid arthritis-induced inflammation that could lead to new drug treatments for people who do not respond to current therapies. Arthritis is Australia’s most common chronic disease and affects more than 3.5 million people. Rheumatoid arthritis (RA) affects about one per cent of the population and is one of the most […]

Continue reading »

Maternal depression may alter stress and immune markers in children

New research suggests that depression in women may affect their children’s stress and physical well-being throughout life. For the Depression & Anxiety study, researchers followed 125 children from birth to 10 years. At 10 years, mothers’ and children’s cortisol (CT) and secretory immunoglobulin (s-IgA)—markers of stress and the immune system—were measured, mother-child interaction were observed, mothers and children underwent psychiatric […]

Continue reading »

Interim guidance provided for men with possible Zika infection

(HealthDay)—Interim guidance recommends that men with possible Zika virus infection wait three months before trying to conceive or engaging in unprotected sex, according to research published in the Aug. 10 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report. Kara D. Polen, M.P.H., from the CDC in Atlanta, and colleagues updated interim guidance for […]

Continue reading »

Large number of presumed sudden cardiac deaths are not

(HealthDay)—A large percentage of deaths attributed to cardiac arrest are neither sudden nor unexpected, according to a study published recently in Circulation. Zian H. Tseng, M.D., from the University of California in San Francisco, and colleagues identified all incident deaths attributed to out-of-hospital cardiac arrest (patients between 18 and 90 years of age in San Francisco County) based on autopsy, […]

Continue reading »

First in-depth profile of CAR T-cell signals suggests how to improve immunotherapy

CAR T-cell therapy, which reprograms immune cells to fight cancer, has shown great promise in people with some blood cancers who have not responded to other treatments. But until now, the underlying biological pathways enabling anti-cancer responses have not been thoroughly examined. Understanding these pathways is important for designing future generations of CAR T-cell therapies, including reducing side effects, preventing […]

Continue reading »

New compound advances into Phase 1 trial for pancreatic cancer

A compound discovered at Sanford Burnham Prebys Medical Discovery Institute (SBP) has advanced into a Phase 1 trial for metastatic pancreatic cancer. Called CEND-1 (scientifically known as iRGD), the compound was exclusively licensed in 2015 to a private company, DrugCendR Inc. The drug candidate was discovered in the laboratory of Erkki Ruoslahti, M.D., Ph.D., distinguished professor at SBP and founder, […]

Continue reading »
1 118 119 120 121 122 202