New target could prevent progression of liver damage to cancer

Problems like obesity and alcoholism appear to chronically trigger in the liver a receptor known to amplify inflammation in response to invaders like bacteria, scientists report. The relentless, increased activity of TREM-1 in turn accelerates injury and scarring of the liver, a first step toward cirrhosis and liver cancer, says Dr. Anatolij Horuzsko, reproductive immunologist in the Georgia Cancer Center […]

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Oxygen therapy for patients suffering from a heart attack does not prevent heart failure

Oxygen therapy does not prevent the development of heart failure. Neither does it reduce the long-term risk of dying for patients with suspected heart attack. This has been proven for the first time by researchers at Karolinska Institutet as a result of a major Swedish study. The study is to be presented at the European Society of Cardiology’s (ESC) cardiology […]

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Research discovers new channel-gating mechanism

Computational biophysicists are not used to making discoveries, says Jianhan Chen at the University of Massachusetts Amherst, so when he and colleagues cracked the secret of how cells regulate Big Potassium (BK) channels, they thought it must be a computational artifact. But after many simulations and tests, they convinced themselves that they have identified the BK gating mechanism that had […]

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Traumatic brain injury recovery via petri dish

Researchers in the University of Georgia’s Regenerative Bioscience Center have succeeded in reproducing the effects of traumatic brain injury and stimulating recovery in neuron cells grown in a petri dish. This makes them the first known scientific team in the country to do so using stem cell-derived neurons. The procedure, detailed in a new paper in Nature Scientific Reports, has […]

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Blood vessels instruct brain development

Function and homeostasis of the brain relies on communication between its complex network of cells. Consequently, development of the different groups of cells in the brain needs to be coordinated in time and space. The group of Amparo Acker-Palmer (Buchmann Institute of Molecular Life Sciences and the Institute of Cell Biology and Neuroscience, Goethe University) reported in the last issue […]

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Treatment for severe heartburn prevents cancer

Medical or surgical treatment of severe heartburn prevents cancer of the oesophagus, a study from Karolinska Institutet with almost one million Nordic patients reveals. The results are published in the scientific journal JAMA Oncology. Pathological heartburn and acid reflux affects 10-20 per cent of the adult population. Long and severe reflux is the strongest risk factor for cancer of the […]

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Strategies for working through daily stress

Stress affects most Americans at one point or another. Although some people are genetically more susceptible to the stressors of daily life than others, most could benefit from learning how to lower that stress before it negatively affects their physical and mental health. Julie Radico, a psychologist and behavioral scientist at Penn State Health Milton S. Hershey Medical Center, said […]

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Q&A: Lung cancer symptoms and prevention

Dear Mayo Clinic: Are there ever any early signs of lung cancer, or is it usually found only in the later stages? Can anything be done to prevent it other than not smoking? A: It’s rare for lung cancer to trigger symptoms before it progresses to its later stages. Most cases of early-stage lung cancer are detected by chance in […]

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Natural sugar defends against metabolic syndrome, in mice

New research, in mice, indicates that a natural sugar called trehalose blocks glucose from the liver and activates a gene that boosts insulin sensitivity, reducing the chance of developing diabetes. Activating the gene also triggers an increase in calories burned, reduces fat accumulation and weight gain, and lessens measures of fats and cholesterol in the blood. The findings, from researchers […]

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