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Alice Hinrichs woke up feeling miserable. She was exhausted, nauseated and her left arm hurt. She thought she was sick, so she called her doctor’s office for an appointment. Instead, her doctor urged her to go to a hospital in case her symptoms were warnings for a heart attack. There, she was stunned to learn she had several serious health […]
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A new study from molecular biologists at Indiana University has identified cellular processes that appear to supercharge both the growth and shrinkage of the chemical “caps” on chromosomes associated with aging, called telomeres. The work, focused on two enzymes in yeast, could lead to new insights on stopping runaway cellular growth in cancer tumors, as well as the treatment of […]
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Results of a 275-patient, multi-national phase III clinical trial known as ALTA-1L published today in the New England Journal of Medicine and presented concurrently in the press program at the International Association for the Study of Lung Cancer (IASLC) World Conference on Lung Cancer 2018 argue for brigatinib as a first-line treatment option for advanced ALK-positive non-small cell lung cancer. […]
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Halfway up a hill overlooking the Great Rift Valley in western Kenya are two graves. One of them is a few years old now, bristling with bushy shrubs stretching bright green leaves towards a cloudless sky. The other is a freshly dug bed of rough red dirt planted with a white wooden cross. They are the final resting places of […]
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According to EU legislation, clinical trials must be prospectively registered in the European Union Clinical Trials Register (EUCTR) and the main results must be reported there one year after completion of the trial. The information is thus publicly available. But in fact, results are only reported for half of drug trials (49.5 percent). According to an analysis recently published in […]
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(HealthDay)—American teens whose behavior, appearance or lifestyle do not conform to widely held views on what it is to be a “normal” male or female face a high risk for mental distress and drug abuse, new research warns. The findings were culled from a national survey exploring the psychological risk profiles of teens who described themselves as “gender nonconforming.” The […]
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An MRI scan often generates an ocean of data, most of which is never used. When overlooked data is analyzed using a new technique developed at Washington University School of Medicine in St. Louis, they surprisingly reveal how many and which brain cells are present – and show where cells have been lost through injury or disease. The findings, published […]
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People who include a little yoga or tai chi in their day may be more likely to remember where they put their keys. Researchers at the University of California, Irvine and Japan’s University of Tsukuba found that even very light workouts can increase the connectivity between parts of the brain responsible for memory formation and storage. In a study of […]
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In the largest multi-institutional study to date, led by researchers from Penn Medicine, the team found that among patients who underwent a transcatheter aortic valve replacement (TAVR), a high number experienced severe and moderate cases of prosthesis-patient mismatch (PPM)—meaning the implanted heart valve is too small for the patient which can lead to inadequate blood flow. The team also found […]
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Researchers examined participation and weight loss results in an online diabetes prevention program; an in-person diabetes prevention program; and the Veterans Administration’s face-to-face standard-of-care weight management program, called MOVE! In the primary analysis, enrollees in the online diabetes prevention program saw a mean weight loss of 10.3 pounds at 6 months and 8.8 pounds at 12 months. In a secondary […]
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