Health Problems Archives - Page 106 of 202

Mouse study mirrors human findings that link chemotherapy and APOE4 to cognitive issues

05.10.2018 Health Problems

The research, led by Georgetown University Medical Center (GUMC) investigators and published in Neurotoxicity Research, complements findings from another GUMC-led study, published Oct. 3, that found a subset of breast cancer patients who experience long lasting cognitive deficits also have the APOE4 gene. Cancer survivors often report memory difficulties and this study, published in the Journal of Clinical Oncology (JCO), […]

How astrophysics could transform the treatment of cystic fibrosis and other rare diseases

05.10.2018 Health Problems

It’s a cruel disease which dramatically shortens life expectancy. One in 25 Europeans carry the cystic fibrosis gene and, in the UK, about 10,400 people currently have the condition. But people are living longer and longer thanks to improvements in screening at birth, early treatment and medication. One of the most important things is for patients to be put on […]

AI could predict cognitive decline leading to Alzheimer’s disease in the next five years

05.10.2018 Health Problems

A team of scientists has successfully trained a new artificial intelligence (AI) algorithm to make accurate predictions regarding cognitive decline leading to Alzheimer’s disease. Dr. Mallar Chakravarty, a computational neuroscientist at the Douglas Mental Health University Institute, and his colleagues from the University of Toronto and the Centre for Addiction and Mental Health, designed an algorithm that learns signatures from […]

Phage therapy draws renewed interest to combat drug-resistant microbes

05.10.2018 Health Problems

The married professors were spending their Thanksgiving holiday in Egypt when the husband, Thomas L. Patterson, Ph.D., got very sick very quickly, experiencing fever, nausea and a racing heartbeat. By the time Patterson was accurately diagnosed with a highly multi-drug resistant bacterial infection, he was near death. His wife, Steffanie Strathdee, Ph.D., promised to “leave no stone unturned.’” What happened […]

Child abuse could leave ‘molecular scars’ on its victims

05.10.2018 Health Problems

Children who are abused might carry the imprint of that trauma in their cells—a biochemical marking that is detectable years later, according to new research from the University of British Columbia and Harvard University. The findings, based on a comparison of chemical tags on the DNA of 34 adult men, still need confirmation from larger studies, and researchers don’t know […]

New clues about how our body guards against cancer

05.10.2018 Health Problems

Walter and Eliza Hall Institute researchers have uncovered a key factor protecting against age-related DNA damage, providing important clues about how our body guards against cancer. The discovery was made by identifying a rare genetic mutation in three patients with an unusual, early-onset form of acute myeloid leukaemia (AML). The patients all lacked a DNA repair protein called MBD4, which […]

Stem cells control their own fate, making lab-grown tissues less effective

05.10.2018 Health Problems

Tissues grown in the lab from stem cells may fail to live up their therapeutic promise because the cells choose their own fate. For the last 20 years, scientists have worked to engineer tissues for use in a range of conditions, such as osteoarthritis or heart failure. They do this by placing stem cells – those that can become any […]

Duvelisib has marked response, survival benefit in difficult-to-treat leukemia and lymphoma

05.10.2018 Health Problems

For some patients with difficult-to-treat leukemia and lymphoma, the investigational oral medicine duvelisib may significantly improve disease outcomes, according to phase III trial data published today in the journal Blood. The DUO trial studied the head-to-head comparison of duvelisib versus ofatumumab, an approved standard-of-care chemotherapy for relapsed or treatment-resistant chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). According to […]

US, Japanese pair win Nobel Medicine Prize for cancer therapy

05.10.2018 Health Problems

Two immunologists, James Allison of the US and Tasuku Honjo of Japan, won the 2018 Nobel Medicine Prize for research that has revolutionised the treatment of cancer, the jury said on Monday. The pair were honoured “for their discovery of cancer therapy by inhibition of negative immune regulation,” the Nobel Assembly said. Immune checkpoint inhibitor therapy targets proteins made by […]

Study reveals large regional variations on future trends of diabetes dependent on if obesity rates are tackled

04.10.2018 Health Problems

New research presented at this year’s annual meeting of the European Association for the Study of Diabetes (EASD) in Berlin looks into the rising prevalence of both obesity and type 2 diabetes (T2D) around the world and estimates the population that will likely be affected by both conditions over the coming decades. The research conducted by University College London, Steno […]

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